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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: THADA All Species: 19.39
Human Site: S984 Identified Species: 42.67
UniProt: Q6YHU6 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6YHU6 NP_001077422.1 1953 219607 S984 P M D T D S E S A S R L Q M I
Chimpanzee Pan troglodytes XP_001141732 1953 219528 S984 P M D T D S E S A S R L Q M I
Rhesus Macaque Macaca mulatta
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus A8C756 1938 217270 S975 P V D T D S A S A S R L Q L I
Rat Rattus norvegicus XP_233829 1937 217220 S975 P M D T D S E S A S R L Q V I
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513110 1056 113729 G169 V L L F L C Q G A L A M L D W
Chicken Gallus gallus A8C754 1930 216561 T976 P M D I D S E T A D R L H M I
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_608361 1746 197334 S859 S V V L P V V S S A S P E G H
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_797130 1666 185673 L779 G L E S P K K L Q D R Y R V A
Poplar Tree Populus trichocarpa XP_002305983 2134 240562 L990 V S A D A W Y L A D M D E M A
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_191076 2149 242725 L986 V S A D A L C L P E D M D D I
Baker's Yeast Sacchar. cerevisiae Q03496 1420 163559 T533 N A L K W T A T S L L S D Y E
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.1 N.A. N.A. N.A. 78.4 79.2 N.A. 30.9 58.1 N.A. N.A. N.A. 21.7 N.A. N.A. 23.4
Protein Similarity: 100 99.4 N.A. N.A. N.A. 87.4 87.5 N.A. 39.8 73 N.A. N.A. N.A. 40.1 N.A. N.A. 40.5
P-Site Identity: 100 100 N.A. N.A. N.A. 80 93.3 N.A. 6.6 73.3 N.A. N.A. N.A. 6.6 N.A. N.A. 6.6
P-Site Similarity: 100 100 N.A. N.A. N.A. 93.3 100 N.A. 26.6 80 N.A. N.A. N.A. 33.3 N.A. N.A. 46.6
Percent
Protein Identity: 20.4 N.A. N.A. 20.8 21.2 N.A.
Protein Similarity: 39 N.A. N.A. 39.9 38.7 N.A.
P-Site Identity: 13.3 N.A. N.A. 6.6 0 N.A.
P-Site Similarity: 20 N.A. N.A. 13.3 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 19 0 19 0 19 0 64 10 10 0 0 0 19 % A
% Cys: 0 0 0 0 0 10 10 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 46 19 46 0 0 0 0 28 10 10 19 19 0 % D
% Glu: 0 0 10 0 0 0 37 0 0 10 0 0 19 0 10 % E
% Phe: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 10 0 0 0 0 0 0 10 0 0 0 0 0 10 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 10 % H
% Ile: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 55 % I
% Lys: 0 0 0 10 0 10 10 0 0 0 0 0 0 0 0 % K
% Leu: 0 19 19 10 10 10 0 28 0 19 10 46 10 10 0 % L
% Met: 0 37 0 0 0 0 0 0 0 0 10 19 0 37 0 % M
% Asn: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 46 0 0 0 19 0 0 0 10 0 0 10 0 0 0 % P
% Gln: 0 0 0 0 0 0 10 0 10 0 0 0 37 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 55 0 10 0 0 % R
% Ser: 10 19 0 10 0 46 0 46 19 37 10 10 0 0 0 % S
% Thr: 0 0 0 37 0 10 0 19 0 0 0 0 0 0 0 % T
% Val: 28 19 10 0 0 10 10 0 0 0 0 0 0 19 0 % V
% Trp: 0 0 0 0 10 10 0 0 0 0 0 0 0 0 10 % W
% Tyr: 0 0 0 0 0 0 10 0 0 0 0 10 0 10 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _