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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: THADA All Species: 13.94
Human Site: T1715 Identified Species: 30.67
UniProt: Q6YHU6 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6YHU6 NP_001077422.1 1953 219607 T1715 S T T P L F L T N P H P I L E
Chimpanzee Pan troglodytes XP_001141732 1953 219528 T1715 S T T P L F L T N P H P I L E
Rhesus Macaque Macaca mulatta
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus A8C756 1938 217270 T1705 S T A P L F L T S P Q P I L E
Rat Rattus norvegicus XP_233829 1937 217220 T1705 G T A P L F L T S P Q P I L D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513110 1056 113729 T842 E G L V P M D T D A D A A A R
Chicken Gallus gallus A8C754 1930 216561 I1712 S I T S L L L I S E K L V L G
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_608361 1746 197334 S1532 Q R C S E E H S T H Q E A G L
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_797130 1666 185673 E1452 I L K L A K G E V D D G G L H
Poplar Tree Populus trichocarpa XP_002305983 2134 240562 P1865 L S G S C F E P K E A V N M Y
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_191076 2149 242725 S1767 V N L I K Q K S L P S E Q V N
Baker's Yeast Sacchar. cerevisiae Q03496 1420 163559 R1206 D S C S K D F R L A S L E C L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.1 N.A. N.A. N.A. 78.4 79.2 N.A. 30.9 58.1 N.A. N.A. N.A. 21.7 N.A. N.A. 23.4
Protein Similarity: 100 99.4 N.A. N.A. N.A. 87.4 87.5 N.A. 39.8 73 N.A. N.A. N.A. 40.1 N.A. N.A. 40.5
P-Site Identity: 100 100 N.A. N.A. N.A. 80 66.6 N.A. 6.6 33.3 N.A. N.A. N.A. 0 N.A. N.A. 6.6
P-Site Similarity: 100 100 N.A. N.A. N.A. 86.6 80 N.A. 13.3 46.6 N.A. N.A. N.A. 6.6 N.A. N.A. 6.6
Percent
Protein Identity: 20.4 N.A. N.A. 20.8 21.2 N.A.
Protein Similarity: 39 N.A. N.A. 39.9 38.7 N.A.
P-Site Identity: 6.6 N.A. N.A. 6.6 0 N.A.
P-Site Similarity: 20 N.A. N.A. 20 6.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 19 0 10 0 0 0 0 19 10 10 19 10 0 % A
% Cys: 0 0 19 0 10 0 0 0 0 0 0 0 0 10 0 % C
% Asp: 10 0 0 0 0 10 10 0 10 10 19 0 0 0 10 % D
% Glu: 10 0 0 0 10 10 10 10 0 19 0 19 10 0 28 % E
% Phe: 0 0 0 0 0 46 10 0 0 0 0 0 0 0 0 % F
% Gly: 10 10 10 0 0 0 10 0 0 0 0 10 10 10 10 % G
% His: 0 0 0 0 0 0 10 0 0 10 19 0 0 0 10 % H
% Ile: 10 10 0 10 0 0 0 10 0 0 0 0 37 0 0 % I
% Lys: 0 0 10 0 19 10 10 0 10 0 10 0 0 0 0 % K
% Leu: 10 10 19 10 46 10 46 0 19 0 0 19 0 55 19 % L
% Met: 0 0 0 0 0 10 0 0 0 0 0 0 0 10 0 % M
% Asn: 0 10 0 0 0 0 0 0 19 0 0 0 10 0 10 % N
% Pro: 0 0 0 37 10 0 0 10 0 46 0 37 0 0 0 % P
% Gln: 10 0 0 0 0 10 0 0 0 0 28 0 10 0 0 % Q
% Arg: 0 10 0 0 0 0 0 10 0 0 0 0 0 0 10 % R
% Ser: 37 19 0 37 0 0 0 19 28 0 19 0 0 0 0 % S
% Thr: 0 37 28 0 0 0 0 46 10 0 0 0 0 0 0 % T
% Val: 10 0 0 10 0 0 0 0 10 0 0 10 10 10 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _