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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: THADA All Species: 8.48
Human Site: T1898 Identified Species: 18.67
UniProt: Q6YHU6 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6YHU6 NP_001077422.1 1953 219607 T1898 P A A E F V K T V E F T R L R
Chimpanzee Pan troglodytes XP_001141732 1953 219528 T1898 P A A E F V K T V E F T R L R
Rhesus Macaque Macaca mulatta
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus A8C756 1938 217270 S1882 L F R E L P L S A E F L K T V
Rat Rattus norvegicus XP_233829 1937 217220 S1881 L F R E L P L S A E F L K T V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513110 1056 113729 L1005 A K E V I G N L W K G V E N G
Chicken Gallus gallus A8C754 1930 216561 L1877 R A Q D Q A Q L T A R L L T A
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_608361 1746 197334 F1695 V D I I A E P F T T A D A M E
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_797130 1666 185673 C1615 L Q E E D H E C L A K V C E A
Poplar Tree Populus trichocarpa XP_002305983 2134 240562 G2040 D H I E N L G G M H F Y Q Y M
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_191076 2149 242725 Q1937 Q F C C Y H L Q K L P N R D F
Baker's Yeast Sacchar. cerevisiae Q03496 1420 163559 S1369 N T E D F K D S P L G W C S N
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.1 N.A. N.A. N.A. 78.4 79.2 N.A. 30.9 58.1 N.A. N.A. N.A. 21.7 N.A. N.A. 23.4
Protein Similarity: 100 99.4 N.A. N.A. N.A. 87.4 87.5 N.A. 39.8 73 N.A. N.A. N.A. 40.1 N.A. N.A. 40.5
P-Site Identity: 100 100 N.A. N.A. N.A. 20 20 N.A. 0 6.6 N.A. N.A. N.A. 0 N.A. N.A. 6.6
P-Site Similarity: 100 100 N.A. N.A. N.A. 33.3 33.3 N.A. 6.6 20 N.A. N.A. N.A. 6.6 N.A. N.A. 20
Percent
Protein Identity: 20.4 N.A. N.A. 20.8 21.2 N.A.
Protein Similarity: 39 N.A. N.A. 39.9 38.7 N.A.
P-Site Identity: 13.3 N.A. N.A. 6.6 6.6 N.A.
P-Site Similarity: 33.3 N.A. N.A. 13.3 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 28 19 0 10 10 0 0 19 19 10 0 10 0 19 % A
% Cys: 0 0 10 10 0 0 0 10 0 0 0 0 19 0 0 % C
% Asp: 10 10 0 19 10 0 10 0 0 0 0 10 0 10 0 % D
% Glu: 0 0 28 55 0 10 10 0 0 37 0 0 10 10 10 % E
% Phe: 0 28 0 0 28 0 0 10 0 0 46 0 0 0 10 % F
% Gly: 0 0 0 0 0 10 10 10 0 0 19 0 0 0 10 % G
% His: 0 10 0 0 0 19 0 0 0 10 0 0 0 0 0 % H
% Ile: 0 0 19 10 10 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 10 0 0 0 10 19 0 10 10 10 0 19 0 0 % K
% Leu: 28 0 0 0 19 10 28 19 10 19 0 28 10 19 0 % L
% Met: 0 0 0 0 0 0 0 0 10 0 0 0 0 10 10 % M
% Asn: 10 0 0 0 10 0 10 0 0 0 0 10 0 10 10 % N
% Pro: 19 0 0 0 0 19 10 0 10 0 10 0 0 0 0 % P
% Gln: 10 10 10 0 10 0 10 10 0 0 0 0 10 0 0 % Q
% Arg: 10 0 19 0 0 0 0 0 0 0 10 0 28 0 19 % R
% Ser: 0 0 0 0 0 0 0 28 0 0 0 0 0 10 0 % S
% Thr: 0 10 0 0 0 0 0 19 19 10 0 19 0 28 0 % T
% Val: 10 0 0 10 0 19 0 0 19 0 0 19 0 0 19 % V
% Trp: 0 0 0 0 0 0 0 0 10 0 0 10 0 0 0 % W
% Tyr: 0 0 0 0 10 0 0 0 0 0 0 10 0 10 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _