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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: THADA All Species: 5.15
Human Site: T1929 Identified Species: 11.33
UniProt: Q6YHU6 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6YHU6 NP_001077422.1 1953 219607 T1929 E G K E G E D T L V L S V W D
Chimpanzee Pan troglodytes XP_001141732 1953 219528 T1929 E G K E G E D T L V L S V W D
Rhesus Macaque Macaca mulatta
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus A8C756 1938 217270 K1914 L L A C L E G K E G L R A E D
Rat Rattus norvegicus XP_233829 1937 217220 K1913 L L A C L E G K E V L R A E D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513110 1056 113729 G1033 P L P G Y L R G E S E D L C P
Chicken Gallus gallus A8C754 1930 216561 I1907 L A I Q N E Q I S L C L K I L
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_608361 1746 197334 W1723 N H V L T E L W D A R G R A D
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_797130 1666 185673 S1643 P S S S S S S S P L G V E P K
Poplar Tree Populus trichocarpa XP_002305983 2134 240562 M2069 N R N I E D D M L L L S Q I V
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_191076 2149 242725 A2072 E I W E A E P A L L L S A K V
Baker's Yeast Sacchar. cerevisiae Q03496 1420 163559 D1397 I Q H Y S P S D Y E N F I N V
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.1 N.A. N.A. N.A. 78.4 79.2 N.A. 30.9 58.1 N.A. N.A. N.A. 21.7 N.A. N.A. 23.4
Protein Similarity: 100 99.4 N.A. N.A. N.A. 87.4 87.5 N.A. 39.8 73 N.A. N.A. N.A. 40.1 N.A. N.A. 40.5
P-Site Identity: 100 100 N.A. N.A. N.A. 20 26.6 N.A. 0 6.6 N.A. N.A. N.A. 13.3 N.A. N.A. 0
P-Site Similarity: 100 100 N.A. N.A. N.A. 20 26.6 N.A. 6.6 20 N.A. N.A. N.A. 13.3 N.A. N.A. 13.3
Percent
Protein Identity: 20.4 N.A. N.A. 20.8 21.2 N.A.
Protein Similarity: 39 N.A. N.A. 39.9 38.7 N.A.
P-Site Identity: 26.6 N.A. N.A. 40 0 N.A.
P-Site Similarity: 40 N.A. N.A. 46.6 6.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 19 0 10 0 0 10 0 10 0 0 28 10 0 % A
% Cys: 0 0 0 19 0 0 0 0 0 0 10 0 0 10 0 % C
% Asp: 0 0 0 0 0 10 28 10 10 0 0 10 0 0 46 % D
% Glu: 28 0 0 28 10 64 0 0 28 10 10 0 10 19 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % F
% Gly: 0 19 0 10 19 0 19 10 0 10 10 10 0 0 0 % G
% His: 0 10 10 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 10 10 10 10 0 0 0 10 0 0 0 0 10 19 0 % I
% Lys: 0 0 19 0 0 0 0 19 0 0 0 0 10 10 10 % K
% Leu: 28 28 0 10 19 10 10 0 37 37 55 10 10 0 10 % L
% Met: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % M
% Asn: 19 0 10 0 10 0 0 0 0 0 10 0 0 10 0 % N
% Pro: 19 0 10 0 0 10 10 0 10 0 0 0 0 10 10 % P
% Gln: 0 10 0 10 0 0 10 0 0 0 0 0 10 0 0 % Q
% Arg: 0 10 0 0 0 0 10 0 0 0 10 19 10 0 0 % R
% Ser: 0 10 10 10 19 10 19 10 10 10 0 37 0 0 0 % S
% Thr: 0 0 0 0 10 0 0 19 0 0 0 0 0 0 0 % T
% Val: 0 0 10 0 0 0 0 0 0 28 0 10 19 0 28 % V
% Trp: 0 0 10 0 0 0 0 10 0 0 0 0 0 19 0 % W
% Tyr: 0 0 0 10 10 0 0 0 10 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _