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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: THADA All Species: 16.97
Human Site: Y395 Identified Species: 37.33
UniProt: Q6YHU6 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6YHU6 NP_001077422.1 1953 219607 Y395 I V G R L L E Y V Y T H W E H
Chimpanzee Pan troglodytes XP_001141732 1953 219528 Y395 I V G R L L E Y V Y T H W E H
Rhesus Macaque Macaca mulatta
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus A8C756 1938 217270 Y395 V P R R L L E Y V Y T H W E H
Rat Rattus norvegicus XP_233829 1937 217220 Y395 I P R R L L E Y V Y T H W E H
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513110 1056 113729
Chicken Gallus gallus A8C754 1930 216561 Y397 V V G K L L E Y V Y T H W E H
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_608361 1746 197334 M293 E Q D V P I Q M A A L L V L R
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_797130 1666 185673 L213 P R D L V Q D L G Q G D T A L
Poplar Tree Populus trichocarpa XP_002305983 2134 240562 M379 Y E P I P V E M G T R I L K I
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_191076 2149 242725 P401 S E G Y D P M P D S M A A R V
Baker's Yeast Sacchar. cerevisiae Q03496 1420 163559
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.1 N.A. N.A. N.A. 78.4 79.2 N.A. 30.9 58.1 N.A. N.A. N.A. 21.7 N.A. N.A. 23.4
Protein Similarity: 100 99.4 N.A. N.A. N.A. 87.4 87.5 N.A. 39.8 73 N.A. N.A. N.A. 40.1 N.A. N.A. 40.5
P-Site Identity: 100 100 N.A. N.A. N.A. 80 86.6 N.A. 0 86.6 N.A. N.A. N.A. 0 N.A. N.A. 0
P-Site Similarity: 100 100 N.A. N.A. N.A. 86.6 86.6 N.A. 0 100 N.A. N.A. N.A. 13.3 N.A. N.A. 13.3
Percent
Protein Identity: 20.4 N.A. N.A. 20.8 21.2 N.A.
Protein Similarity: 39 N.A. N.A. 39.9 38.7 N.A.
P-Site Identity: 6.6 N.A. N.A. 6.6 0 N.A.
P-Site Similarity: 20 N.A. N.A. 6.6 0 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 10 10 0 10 10 10 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 19 0 10 0 10 0 10 0 0 10 0 0 0 % D
% Glu: 10 19 0 0 0 0 55 0 0 0 0 0 0 46 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 37 0 0 0 0 0 19 0 10 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 46 0 0 46 % H
% Ile: 28 0 0 10 0 10 0 0 0 0 0 10 0 0 10 % I
% Lys: 0 0 0 10 0 0 0 0 0 0 0 0 0 10 0 % K
% Leu: 0 0 0 10 46 46 0 10 0 0 10 10 10 10 10 % L
% Met: 0 0 0 0 0 0 10 19 0 0 10 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 10 19 10 0 19 10 0 10 0 0 0 0 0 0 0 % P
% Gln: 0 10 0 0 0 10 10 0 0 10 0 0 0 0 0 % Q
% Arg: 0 10 19 37 0 0 0 0 0 0 10 0 0 10 10 % R
% Ser: 10 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 10 46 0 10 0 0 % T
% Val: 19 28 0 10 10 10 0 0 46 0 0 0 10 0 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 46 0 0 % W
% Tyr: 10 0 0 10 0 0 0 46 0 46 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _