KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
THADA
All Species:
20.61
Human Site:
Y548
Identified Species:
45.33
UniProt:
Q6YHU6
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6YHU6
NP_001077422.1
1953
219607
Y548
Q
K
S
Y
V
I
D
Y
Y
L
P
K
L
L
S
Chimpanzee
Pan troglodytes
XP_001141732
1953
219528
Y548
Q
K
S
Y
V
I
D
Y
Y
L
P
K
L
L
S
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
A8C756
1938
217270
Y548
Q
R
S
Y
V
I
D
Y
Y
L
P
R
I
L
N
Rat
Rattus norvegicus
XP_233829
1937
217220
Y548
Q
R
S
Y
V
I
D
Y
Y
L
P
R
L
L
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513110
1056
113729
Chicken
Gallus gallus
A8C754
1930
216561
Y550
Q
T
T
Y
I
I
D
Y
Y
L
P
K
L
L
R
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_608361
1746
197334
S440
A
V
A
G
V
S
K
S
I
E
N
C
P
S
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_797130
1666
185673
G360
R
G
K
Y
G
P
L
G
C
I
F
E
M
E
G
Poplar Tree
Populus trichocarpa
XP_002305983
2134
240562
Y540
L
R
S
N
V
N
T
Y
A
L
P
V
L
L
E
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_191076
2149
242725
N561
G
K
S
K
L
R
S
N
L
N
T
Y
A
V
Q
Baker's Yeast
Sacchar. cerevisiae
Q03496
1420
163559
L114
N
I
I
F
E
Y
V
L
D
F
W
A
D
G
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
N.A.
N.A.
N.A.
78.4
79.2
N.A.
30.9
58.1
N.A.
N.A.
N.A.
21.7
N.A.
N.A.
23.4
Protein Similarity:
100
99.4
N.A.
N.A.
N.A.
87.4
87.5
N.A.
39.8
73
N.A.
N.A.
N.A.
40.1
N.A.
N.A.
40.5
P-Site Identity:
100
100
N.A.
N.A.
N.A.
73.3
80
N.A.
0
73.3
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
6.6
P-Site Similarity:
100
100
N.A.
N.A.
N.A.
100
100
N.A.
0
86.6
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
33.3
Percent
Protein Identity:
20.4
N.A.
N.A.
20.8
21.2
N.A.
Protein Similarity:
39
N.A.
N.A.
39.9
38.7
N.A.
P-Site Identity:
46.6
N.A.
N.A.
13.3
0
N.A.
P-Site Similarity:
53.3
N.A.
N.A.
26.6
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
10
0
0
0
0
0
10
0
0
10
10
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
10
0
0
10
0
0
0
% C
% Asp:
0
0
0
0
0
0
46
0
10
0
0
0
10
0
0
% D
% Glu:
0
0
0
0
10
0
0
0
0
10
0
10
0
10
10
% E
% Phe:
0
0
0
10
0
0
0
0
0
10
10
0
0
0
0
% F
% Gly:
10
10
0
10
10
0
0
10
0
0
0
0
0
10
19
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
10
10
0
10
46
0
0
10
10
0
0
10
0
0
% I
% Lys:
0
28
10
10
0
0
10
0
0
0
0
28
0
0
0
% K
% Leu:
10
0
0
0
10
0
10
10
10
55
0
0
46
55
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% M
% Asn:
10
0
0
10
0
10
0
10
0
10
10
0
0
0
19
% N
% Pro:
0
0
0
0
0
10
0
0
0
0
55
0
10
0
0
% P
% Gln:
46
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% Q
% Arg:
10
28
0
0
0
10
0
0
0
0
0
19
0
0
10
% R
% Ser:
0
0
55
0
0
10
10
10
0
0
0
0
0
10
19
% S
% Thr:
0
10
10
0
0
0
10
0
0
0
10
0
0
0
0
% T
% Val:
0
10
0
0
55
0
10
0
0
0
0
10
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% W
% Tyr:
0
0
0
55
0
10
0
55
46
0
0
10
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _