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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TMEM64 All Species: 14.24
Human Site: Y291 Identified Species: 39.17
UniProt: Q6YI46 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6YI46 NP_001008495.2 380 39665 Y291 P T Q L L N S Y L G T T L R T
Chimpanzee Pan troglodytes XP_528186 186 19928 M105 L G T T L R T M E D V I A E Q
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_544169 186 19850 M105 L G T T L R T M E D V I A E Q
Cat Felis silvestris
Mouse Mus musculus Q3U145 381 39796 Y292 P T Q L L N S Y L G T T L R T
Rat Rattus norvegicus XP_002725628 292 30476 V211 G G S G L K V V A L A R L T P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518375 115 12394 T33 Y L G T T L R T M E D V I A E
Chicken Gallus gallus XP_001234281 363 37938 Y273 P T Q L L N S Y L G T T L R T
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001121723 348 37133 Y260 P T Q L L N S Y L G T T L R T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_397355 285 31091 L204 A Q I I N I Y L G S S L R S M
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 48.9 N.A. 46.5 N.A. 89.2 67.1 N.A. 26.5 69.7 N.A. 63.4 N.A. N.A. 26.8 N.A. N.A.
Protein Similarity: 100 48.9 N.A. 48.4 N.A. 92.6 69.7 N.A. 28.9 77.3 N.A. 73.9 N.A. N.A. 47.6 N.A. N.A.
P-Site Identity: 100 6.6 N.A. 6.6 N.A. 100 13.3 N.A. 0 100 N.A. 100 N.A. N.A. 0 N.A. N.A.
P-Site Similarity: 100 13.3 N.A. 13.3 N.A. 100 13.3 N.A. 13.3 100 N.A. 100 N.A. N.A. 13.3 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 12 0 0 0 0 0 0 0 12 0 12 0 23 12 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 23 12 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 23 12 0 0 0 23 12 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 12 34 12 12 0 0 0 0 12 45 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 12 12 0 12 0 0 0 0 0 23 12 0 0 % I
% Lys: 0 0 0 0 0 12 0 0 0 0 0 0 0 0 0 % K
% Leu: 23 12 0 45 78 12 0 12 45 12 0 12 56 0 0 % L
% Met: 0 0 0 0 0 0 0 23 12 0 0 0 0 0 12 % M
% Asn: 0 0 0 0 12 45 0 0 0 0 0 0 0 0 0 % N
% Pro: 45 0 0 0 0 0 0 0 0 0 0 0 0 0 12 % P
% Gln: 0 12 45 0 0 0 0 0 0 0 0 0 0 0 23 % Q
% Arg: 0 0 0 0 0 23 12 0 0 0 0 12 12 45 0 % R
% Ser: 0 0 12 0 0 0 45 0 0 12 12 0 0 12 0 % S
% Thr: 0 45 23 34 12 0 23 12 0 0 45 45 0 12 45 % T
% Val: 0 0 0 0 0 0 12 12 0 0 23 12 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 12 0 0 0 0 0 12 45 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _