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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HSDL2
All Species:
25.45
Human Site:
S322
Identified Species:
50.91
UniProt:
Q6YN16
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6YN16
NP_115679.2
418
45395
S322
R
I
V
K
D
S
L
S
D
D
V
V
K
A
T
Chimpanzee
Pan troglodytes
XP_001149879
344
37375
P267
Y
A
I
K
P
G
H
P
L
Q
P
D
F
F
L
Rhesus Macaque
Macaca mulatta
XP_001104189
418
45360
S322
R
I
V
K
D
S
L
S
D
D
I
V
K
A
T
Dog
Lupus familis
XP_867643
418
45496
S322
R
I
V
K
D
S
L
S
D
D
I
V
K
A
T
Cat
Felis silvestris
Mouse
Mus musculus
Q2TPA8
490
54190
S394
R
I
V
K
D
S
L
S
D
E
V
V
R
A
T
Rat
Rattus norvegicus
Q4V8F9
524
58325
S428
R
I
V
K
D
S
L
S
D
E
V
V
R
A
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512554
339
36706
N262
L
F
E
L
S
G
E
N
G
G
T
W
Y
L
D
Chicken
Gallus gallus
Frog
Xenopus laevis
Q6PAY8
417
44541
N321
K
A
I
E
R
S
V
N
E
E
A
V
K
S
T
Zebra Danio
Brachydanio rerio
Q6P5L8
415
44402
S319
N
T
I
R
G
I
I
S
P
E
M
V
K
T
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651578
412
44336
S316
R
K
I
E
S
L
L
S
P
E
I
V
S
K
T
Honey Bee
Apis mellifera
XP_625095
413
45255
N317
T
V
I
Q
A
N
L
N
H
E
L
V
N
K
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001199875
478
50542
S322
D
K
M
G
G
M
L
S
E
S
H
V
Q
K
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
81.5
95.9
88.2
N.A.
75.5
69.6
N.A.
58.8
N.A.
73.2
70
N.A.
56.9
55
N.A.
51.8
Protein Similarity:
100
81.8
98.5
94.5
N.A.
81.6
76.3
N.A.
69.6
N.A.
85.4
82
N.A.
72
71.7
N.A.
65
P-Site Identity:
100
6.6
93.3
93.3
N.A.
86.6
86.6
N.A.
0
N.A.
26.6
26.6
N.A.
33.3
13.3
N.A.
20
P-Site Similarity:
100
13.3
100
100
N.A.
100
100
N.A.
6.6
N.A.
80
60
N.A.
60
60
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
17
0
0
9
0
0
0
0
0
9
0
0
42
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
9
0
0
0
42
0
0
0
42
25
0
9
0
0
9
% D
% Glu:
0
0
9
17
0
0
9
0
17
50
0
0
0
0
0
% E
% Phe:
0
9
0
0
0
0
0
0
0
0
0
0
9
9
0
% F
% Gly:
0
0
0
9
17
17
0
0
9
9
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
9
0
9
0
9
0
0
0
0
% H
% Ile:
0
42
42
0
0
9
9
0
0
0
25
0
0
0
17
% I
% Lys:
9
17
0
50
0
0
0
0
0
0
0
0
42
25
0
% K
% Leu:
9
0
0
9
0
9
67
0
9
0
9
0
0
9
9
% L
% Met:
0
0
9
0
0
9
0
0
0
0
9
0
0
0
0
% M
% Asn:
9
0
0
0
0
9
0
25
0
0
0
0
9
0
0
% N
% Pro:
0
0
0
0
9
0
0
9
17
0
9
0
0
0
0
% P
% Gln:
0
0
0
9
0
0
0
0
0
9
0
0
9
0
0
% Q
% Arg:
50
0
0
9
9
0
0
0
0
0
0
0
17
0
0
% R
% Ser:
0
0
0
0
17
50
0
67
0
9
0
0
9
9
0
% S
% Thr:
9
9
0
0
0
0
0
0
0
0
9
0
0
9
67
% T
% Val:
0
9
42
0
0
0
9
0
0
0
25
84
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% W
% Tyr:
9
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _