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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HSDL2
All Species:
29.39
Human Site:
T344
Identified Species:
58.79
UniProt:
Q6YN16
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6YN16
NP_115679.2
418
45395
T344
L
S
G
E
D
G
G
T
W
F
L
D
L
K
S
Chimpanzee
Pan troglodytes
XP_001149879
344
37375
G289
S
K
K
V
E
S
T
G
A
V
P
E
F
K
E
Rhesus Macaque
Macaca mulatta
XP_001104189
418
45360
T344
L
S
G
E
D
G
G
T
W
F
L
D
L
K
S
Dog
Lupus familis
XP_867643
418
45496
T344
L
S
G
E
D
G
G
T
W
F
L
D
L
K
S
Cat
Felis silvestris
Mouse
Mus musculus
Q2TPA8
490
54190
T416
L
S
G
E
D
G
G
T
W
F
L
D
L
K
S
Rat
Rattus norvegicus
Q4V8F9
524
58325
T450
L
S
G
E
D
G
G
T
W
F
L
D
L
K
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512554
339
36706
D284
A
G
Y
G
A
P
P
D
K
V
D
V
V
M
T
Chicken
Gallus gallus
Frog
Xenopus laevis
Q6PAY8
417
44541
N343
L
S
G
E
E
S
G
N
W
F
L
D
L
K
N
Zebra Danio
Brachydanio rerio
Q6P5L8
415
44402
V341
L
A
G
E
H
A
G
V
W
Y
L
D
L
K
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651578
412
44336
T338
I
S
G
A
E
Q
G
T
W
F
L
D
L
K
N
Honey Bee
Apis mellifera
XP_625095
413
45255
T339
V
K
G
N
E
A
G
T
W
F
L
D
L
K
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001199875
478
50542
T344
L
S
G
N
E
P
G
T
W
H
L
D
L
K
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
81.5
95.9
88.2
N.A.
75.5
69.6
N.A.
58.8
N.A.
73.2
70
N.A.
56.9
55
N.A.
51.8
Protein Similarity:
100
81.8
98.5
94.5
N.A.
81.6
76.3
N.A.
69.6
N.A.
85.4
82
N.A.
72
71.7
N.A.
65
P-Site Identity:
100
6.6
100
100
N.A.
100
100
N.A.
0
N.A.
73.3
60
N.A.
66.6
60
N.A.
66.6
P-Site Similarity:
100
20
100
100
N.A.
100
100
N.A.
13.3
N.A.
86.6
80
N.A.
86.6
80
N.A.
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
9
0
9
9
17
0
0
9
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
42
0
0
9
0
0
9
84
0
0
0
% D
% Glu:
0
0
0
59
42
0
0
0
0
0
0
9
0
0
9
% E
% Phe:
0
0
0
0
0
0
0
0
0
67
0
0
9
0
0
% F
% Gly:
0
9
84
9
0
42
84
9
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
9
0
0
0
0
9
0
0
0
0
0
% H
% Ile:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
17
9
0
0
0
0
0
9
0
0
0
0
92
0
% K
% Leu:
67
0
0
0
0
0
0
0
0
0
84
0
84
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% M
% Asn:
0
0
0
17
0
0
0
9
0
0
0
0
0
0
34
% N
% Pro:
0
0
0
0
0
17
9
0
0
0
9
0
0
0
0
% P
% Gln:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
9
67
0
0
0
17
0
0
0
0
0
0
0
0
42
% S
% Thr:
0
0
0
0
0
0
9
67
0
0
0
0
0
0
17
% T
% Val:
9
0
0
9
0
0
0
9
0
17
0
9
9
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
84
0
0
0
0
0
0
% W
% Tyr:
0
0
9
0
0
0
0
0
0
9
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _