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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HSDL2
All Species:
30.61
Human Site:
T387
Identified Species:
61.21
UniProt:
Q6YN16
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6YN16
NP_115679.2
418
45395
T387
F
S
G
K
L
K
P
T
M
A
F
M
S
G
K
Chimpanzee
Pan troglodytes
XP_001149879
344
37375
I332
V
V
K
A
T
Q
A
I
Y
L
F
E
L
S
G
Rhesus Macaque
Macaca mulatta
XP_001104189
418
45360
T387
F
S
G
K
L
K
P
T
M
A
F
M
S
G
K
Dog
Lupus familis
XP_867643
418
45496
T387
F
S
G
K
L
K
P
T
M
A
F
M
S
G
K
Cat
Felis silvestris
Mouse
Mus musculus
Q2TPA8
490
54190
T459
F
S
G
K
L
K
P
T
M
A
F
M
S
G
K
Rat
Rattus norvegicus
Q4V8F9
524
58325
T493
F
S
G
K
L
K
P
T
M
A
F
M
S
G
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512554
339
36706
K327
G
N
M
S
L
A
I
K
L
E
R
L
M
N
Q
Chicken
Gallus gallus
Frog
Xenopus laevis
Q6PAY8
417
44541
T386
F
A
G
K
M
K
P
T
M
A
F
M
S
G
K
Zebra Danio
Brachydanio rerio
Q6P5L8
415
44402
T384
F
G
G
K
L
K
P
T
M
A
F
M
S
G
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651578
412
44336
A381
F
S
G
K
L
K
A
A
P
A
Y
M
T
G
K
Honey Bee
Apis mellifera
XP_625095
413
45255
A382
F
S
G
K
L
K
P
A
S
A
F
L
M
G
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001199875
478
50542
T387
F
E
G
K
I
K
A
T
V
A
F
M
G
G
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
81.5
95.9
88.2
N.A.
75.5
69.6
N.A.
58.8
N.A.
73.2
70
N.A.
56.9
55
N.A.
51.8
Protein Similarity:
100
81.8
98.5
94.5
N.A.
81.6
76.3
N.A.
69.6
N.A.
85.4
82
N.A.
72
71.7
N.A.
65
P-Site Identity:
100
6.6
100
100
N.A.
100
100
N.A.
6.6
N.A.
86.6
93.3
N.A.
66.6
73.3
N.A.
66.6
P-Site Similarity:
100
13.3
100
100
N.A.
100
100
N.A.
33.3
N.A.
100
93.3
N.A.
80
80
N.A.
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
9
0
9
25
17
0
84
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
9
0
0
0
0
0
0
0
9
0
9
0
0
0
% E
% Phe:
84
0
0
0
0
0
0
0
0
0
84
0
0
0
0
% F
% Gly:
9
9
84
0
0
0
0
0
0
0
0
0
9
84
9
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
9
0
9
9
0
0
0
0
0
0
0
% I
% Lys:
0
0
9
84
0
84
0
9
0
0
0
0
0
0
84
% K
% Leu:
0
0
0
0
75
0
0
0
9
9
0
17
9
0
0
% L
% Met:
0
0
9
0
9
0
0
0
59
0
0
75
17
0
0
% M
% Asn:
0
9
0
0
0
0
0
0
0
0
0
0
0
9
0
% N
% Pro:
0
0
0
0
0
0
67
0
9
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
9
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% R
% Ser:
0
59
0
9
0
0
0
0
9
0
0
0
59
9
0
% S
% Thr:
0
0
0
0
9
0
0
67
0
0
0
0
9
0
0
% T
% Val:
9
9
0
0
0
0
0
0
9
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
9
0
9
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _