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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SIGLEC15
All Species:
4.55
Human Site:
T296
Identified Species:
25
UniProt:
Q6ZMC9
Number Species:
4
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6ZMC9
NP_998767.1
328
35653
T296
R
R
P
E
H
L
D
T
P
D
T
P
P
R
S
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001089000
328
35072
T296
H
R
P
E
H
L
N
T
P
D
T
P
P
R
F
Dog
Lupus familis
XP_855238
329
35309
A297
R
R
R
E
H
P
V
A
Q
D
T
P
P
W
P
Cat
Felis silvestris
Mouse
Mus musculus
Rat
Rattus norvegicus
Q8CFD9
192
20452
S161
V
Y
A
L
S
F
L
S
V
A
T
G
S
V
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001095865
287
31136
V256
R
S
S
F
S
L
V
V
L
L
L
A
L
A
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
93.5
83.5
N.A.
N.A.
22.2
N.A.
N.A.
N.A.
N.A.
29.2
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
N.A.
94.5
86.9
N.A.
N.A.
31.7
N.A.
N.A.
N.A.
N.A.
45.1
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
N.A.
80
53.3
N.A.
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
N.A.
86.6
53.3
N.A.
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
20
0
0
0
0
20
0
20
0
20
0
20
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
20
0
0
60
0
0
0
0
0
% D
% Glu:
0
0
0
60
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
20
0
20
0
0
0
0
0
0
0
0
20
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
20
0
0
0
% G
% His:
20
0
0
0
60
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
20
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
20
0
60
20
0
20
20
20
0
20
0
20
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
20
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
40
0
0
20
0
0
40
0
0
60
60
0
20
% P
% Gln:
0
0
0
0
0
0
0
0
20
0
0
0
0
0
0
% Q
% Arg:
60
60
20
0
0
0
0
0
0
0
0
0
0
40
0
% R
% Ser:
0
20
20
0
40
0
0
20
0
0
0
0
20
0
20
% S
% Thr:
0
0
0
0
0
0
0
40
0
0
80
0
0
0
0
% T
% Val:
20
0
0
0
0
0
40
20
20
0
0
0
0
20
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
20
0
% W
% Tyr:
0
20
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _