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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SPNS3 All Species: 3.94
Human Site: T485 Identified Species: 9.63
UniProt: Q6ZMD2 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.22
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6ZMD2 NP_872344.3 512 54769 T485 A W Q P V T G T P D S N D V D
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001117716 307 33109 A281 T G A L G F W A P K F L L E A
Dog Lupus familis XP_848383 549 58719 S479 A R R P S P G S P T P L H P S
Cat Felis silvestris
Mouse Mus musculus Q9D232 514 55438 K487 A R A R Q P G K G T L D S K D
Rat Rattus norvegicus Q2YDU8 528 56778 L499 A Q L H V Q G L L H E T E P S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516336 677 72447 K576 A E R P R S R K Q L G T G R G
Chicken Gallus gallus XP_415741 537 58785 Q503 H W S F C S L Q Y S F I I C V
Frog Xenopus laevis Q5XGK0 526 57788 L497 A E L F S Q G L L P A D E T D
Zebra Danio Brachydanio rerio A2CER7 498 54271 L469 L F F L M T S L Y I K E D R K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9GQQ0 605 65801 S540 E T A R S S A S Q E Y S D V E
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 53.5 73.4 N.A. 78 50 N.A. 42.5 46.9 45 48.8 N.A. 36.3 N.A. N.A. N.A.
Protein Similarity: 100 N.A. 55.6 79.9 N.A. 84.6 64.7 N.A. 53.1 63.5 63.6 66.2 N.A. 50.2 N.A. N.A. N.A.
P-Site Identity: 100 N.A. 6.6 26.6 N.A. 20 20 N.A. 13.3 6.6 20 13.3 N.A. 13.3 N.A. N.A. N.A.
P-Site Similarity: 100 N.A. 6.6 40 N.A. 26.6 26.6 N.A. 26.6 13.3 40 26.6 N.A. 46.6 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 60 0 30 0 0 0 10 10 0 0 10 0 0 0 10 % A
% Cys: 0 0 0 0 10 0 0 0 0 0 0 0 0 10 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 10 0 20 30 0 30 % D
% Glu: 10 20 0 0 0 0 0 0 0 10 10 10 20 10 10 % E
% Phe: 0 10 10 20 0 10 0 0 0 0 20 0 0 0 0 % F
% Gly: 0 10 0 0 10 0 50 0 10 0 10 0 10 0 10 % G
% His: 10 0 0 10 0 0 0 0 0 10 0 0 10 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 10 0 10 10 0 0 % I
% Lys: 0 0 0 0 0 0 0 20 0 10 10 0 0 10 10 % K
% Leu: 10 0 20 20 0 0 10 30 20 10 10 20 10 0 0 % L
% Met: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % N
% Pro: 0 0 0 30 0 20 0 0 30 10 10 0 0 20 0 % P
% Gln: 0 10 10 0 10 20 0 10 20 0 0 0 0 0 0 % Q
% Arg: 0 20 20 20 10 0 10 0 0 0 0 0 0 20 0 % R
% Ser: 0 0 10 0 30 30 10 20 0 10 10 10 10 0 20 % S
% Thr: 10 10 0 0 0 20 0 10 0 20 0 20 0 10 0 % T
% Val: 0 0 0 0 20 0 0 0 0 0 0 0 0 20 10 % V
% Trp: 0 20 0 0 0 0 10 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 20 0 10 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _