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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LASS6 All Species: 30.61
Human Site: S331 Identified Species: 61.21
UniProt: Q6ZMG9 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6ZMG9 NP_982288.1 384 44890 S331 K I A C K A V S R G K V S K D
Chimpanzee Pan troglodytes XP_001154789 392 45775 N339 R G K A G K W N P L H V S K D
Rhesus Macaque Macaca mulatta XP_001102489 384 44902 S331 K I A C K A V S R G K V S K D
Dog Lupus familis XP_545509 450 51784 S397 K I A C K A I S K G K V S K D
Cat Felis silvestris
Mouse Mus musculus Q8C172 384 44794 S331 K I A C K T V S K G K V S K D
Rat Rattus norvegicus XP_001058317 384 44840 S331 K I A C K T V S K G K V S K D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513818 351 40653 S294 K I A C K A I S K G K V S K D
Chicken Gallus gallus XP_001233814 387 45061 S331 K A A Y K A I S K G K V T K D
Frog Xenopus laevis NP_001083908 382 44882 K329 L I L R I A Y K A L V R G K V
Zebra Danio Brachydanio rerio XP_693283 383 44938 S331 R I A C R A I S R G K V S K D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_652526 400 46332 Q334 K I V V D S L Q K G L M S G D
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LDF2 310 36479 L258 K H P N G P I L Y Y M F N T L
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.9 99.4 81.7 N.A. 95.3 95.3 N.A. 77.3 77.5 67.7 78.9 N.A. 39.2 N.A. N.A. N.A.
Protein Similarity: 100 97.9 99.7 84.2 N.A. 97.9 97.9 N.A. 83 88.3 81.7 90.3 N.A. 59.5 N.A. N.A. N.A.
P-Site Identity: 100 26.6 100 86.6 N.A. 86.6 86.6 N.A. 86.6 66.6 20 80 N.A. 33.3 N.A. N.A. N.A.
P-Site Similarity: 100 40 100 100 N.A. 93.3 93.3 N.A. 100 86.6 20 100 N.A. 60 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 22.9 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 42.7 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 20 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 9 67 9 0 59 0 0 9 0 0 0 0 0 0 % A
% Cys: 0 0 0 59 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 9 0 0 0 0 0 0 0 0 0 84 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 9 0 0 0 % F
% Gly: 0 9 0 0 17 0 0 0 0 75 0 0 9 9 0 % G
% His: 0 9 0 0 0 0 0 0 0 0 9 0 0 0 0 % H
% Ile: 0 75 0 0 9 0 42 0 0 0 0 0 0 0 0 % I
% Lys: 75 0 9 0 59 9 0 9 50 0 67 0 0 84 0 % K
% Leu: 9 0 9 0 0 0 9 9 0 17 9 0 0 0 9 % L
% Met: 0 0 0 0 0 0 0 0 0 0 9 9 0 0 0 % M
% Asn: 0 0 0 9 0 0 0 9 0 0 0 0 9 0 0 % N
% Pro: 0 0 9 0 0 9 0 0 9 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 9 0 0 0 0 0 0 0 % Q
% Arg: 17 0 0 9 9 0 0 0 25 0 0 9 0 0 0 % R
% Ser: 0 0 0 0 0 9 0 67 0 0 0 0 75 0 0 % S
% Thr: 0 0 0 0 0 17 0 0 0 0 0 0 9 9 0 % T
% Val: 0 0 9 9 0 0 34 0 0 0 9 75 0 0 9 % V
% Trp: 0 0 0 0 0 0 9 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 9 0 0 9 0 9 9 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _