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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LASS6 All Species: 37.58
Human Site: S341 Identified Species: 75.15
UniProt: Q6ZMG9 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6ZMG9 NP_982288.1 384 44890 S341 K V S K D D R S D I E S S S D
Chimpanzee Pan troglodytes XP_001154789 392 45775 S349 H V S K D D R S D I E S S S D
Rhesus Macaque Macaca mulatta XP_001102489 384 44902 S341 K V S K D D R S D I E S S S D
Dog Lupus familis XP_545509 450 51784 S407 K V S K D D R S D I E S S S D
Cat Felis silvestris
Mouse Mus musculus Q8C172 384 44794 S341 K V S K D D R S D I E S S S D
Rat Rattus norvegicus XP_001058317 384 44840 S341 K V S K D D R S D I E S S S D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513818 351 40653 S304 K V S K D D R S D I E S S S D
Chicken Gallus gallus XP_001233814 387 45061 S341 K V T K D D R S D I E S S S D
Frog Xenopus laevis NP_001083908 382 44882 D339 V R G K V L K D D R S D V E S
Zebra Danio Brachydanio rerio XP_693283 383 44938 S341 K V S K D D R S D I E S S S D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_652526 400 46332 S344 L M S G D I R S S D S E D L T
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LDF2 310 36479 F268 M F N T L L Y F L L V L H I F
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.9 99.4 81.7 N.A. 95.3 95.3 N.A. 77.3 77.5 67.7 78.9 N.A. 39.2 N.A. N.A. N.A.
Protein Similarity: 100 97.9 99.7 84.2 N.A. 97.9 97.9 N.A. 83 88.3 81.7 90.3 N.A. 59.5 N.A. N.A. N.A.
P-Site Identity: 100 93.3 100 100 N.A. 100 100 N.A. 100 93.3 13.3 100 N.A. 26.6 N.A. N.A. N.A.
P-Site Similarity: 100 93.3 100 100 N.A. 100 100 N.A. 100 100 20 100 N.A. 33.3 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 22.9 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 42.7 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 0 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 84 75 0 9 84 9 0 9 9 0 75 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 75 9 0 9 0 % E
% Phe: 0 9 0 0 0 0 0 9 0 0 0 0 0 0 9 % F
% Gly: 0 0 9 9 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 9 0 0 0 0 0 0 0 0 0 0 0 9 0 0 % H
% Ile: 0 0 0 0 0 9 0 0 0 75 0 0 0 9 0 % I
% Lys: 67 0 0 84 0 0 9 0 0 0 0 0 0 0 0 % K
% Leu: 9 0 0 0 9 17 0 0 9 9 0 9 0 9 0 % L
% Met: 9 9 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 9 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 9 0 0 0 0 84 0 0 9 0 0 0 0 0 % R
% Ser: 0 0 75 0 0 0 0 84 9 0 17 75 75 75 9 % S
% Thr: 0 0 9 9 0 0 0 0 0 0 0 0 0 0 9 % T
% Val: 9 75 0 0 9 0 0 0 0 0 9 0 9 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 9 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _