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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LASS6
All Species:
35.76
Human Site:
S345
Identified Species:
71.52
UniProt:
Q6ZMG9
Number Species:
11
Phosphosite Substitution
Charge Score:
0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6ZMG9
NP_982288.1
384
44890
S345
D
D
R
S
D
I
E
S
S
S
D
E
E
D
S
Chimpanzee
Pan troglodytes
XP_001154789
392
45775
S353
D
D
R
S
D
I
E
S
S
S
D
E
E
D
S
Rhesus Macaque
Macaca mulatta
XP_001102489
384
44902
S345
D
D
R
S
D
I
E
S
S
S
D
E
E
D
S
Dog
Lupus familis
XP_545509
450
51784
S411
D
D
R
S
D
I
E
S
S
S
D
E
E
D
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8C172
384
44794
S345
D
D
R
S
D
I
E
S
S
S
D
D
E
D
S
Rat
Rattus norvegicus
XP_001058317
384
44840
S345
D
D
R
S
D
I
E
S
S
S
D
D
E
D
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513818
351
40653
S308
D
D
R
S
D
I
E
S
S
S
D
E
E
G
S
Chicken
Gallus gallus
XP_001233814
387
45061
S345
D
D
R
S
D
I
E
S
S
S
D
E
E
E
T
Frog
Xenopus laevis
NP_001083908
382
44882
D343
V
L
K
D
D
R
S
D
V
E
S
S
S
E
E
Zebra Danio
Brachydanio rerio
XP_693283
383
44938
S345
D
D
R
S
D
I
E
S
S
S
D
E
D
E
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_652526
400
46332
E348
D
I
R
S
S
D
S
E
D
L
T
D
S
S
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LDF2
310
36479
L272
L
L
Y
F
L
L
V
L
H
I
F
W
W
V
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.9
99.4
81.7
N.A.
95.3
95.3
N.A.
77.3
77.5
67.7
78.9
N.A.
39.2
N.A.
N.A.
N.A.
Protein Similarity:
100
97.9
99.7
84.2
N.A.
97.9
97.9
N.A.
83
88.3
81.7
90.3
N.A.
59.5
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
93.3
93.3
N.A.
93.3
86.6
6.6
80
N.A.
20
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
93.3
100
20
93.3
N.A.
26.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
22.9
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
42.7
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
84
75
0
9
84
9
0
9
9
0
75
25
9
50
0
% D
% Glu:
0
0
0
0
0
0
75
9
0
9
0
59
67
25
9
% E
% Phe:
0
0
0
9
0
0
0
0
0
0
9
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
9
% G
% His:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% H
% Ile:
0
9
0
0
0
75
0
0
0
9
0
0
0
0
0
% I
% Lys:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
9
17
0
0
9
9
0
9
0
9
0
0
0
0
17
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
84
0
0
9
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
84
9
0
17
75
75
75
9
9
17
9
59
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
9
% T
% Val:
9
0
0
0
0
0
9
0
9
0
0
0
0
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
9
9
0
0
% W
% Tyr:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _