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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SLC39A5 All Species: 6.06
Human Site: S114 Identified Species: 12.12
UniProt: Q6ZMH5 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6ZMH5 NP_001128667.1 539 56330 S114 A G M P L G P S G W G D L E E
Chimpanzee Pan troglodytes XP_509141 540 56446 S115 A G M P L G P S G W G D L E E
Rhesus Macaque Macaca mulatta XP_001114684 546 57047 S121 S D L P A S A S Q S A G T T D
Dog Lupus familis XP_538229 449 46237 V103 S Q D P E L S V D V W A G L P
Cat Felis silvestris
Mouse Mus musculus Q9D856 535 56257 P113 W A G M P L G P S G W G D Q E
Rat Rattus norvegicus A0JPN2 656 71103 V234 D L M H H L G V G G E D H S D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519251 329 34223
Chicken Gallus gallus Q5ZI20 366 39255 C20 S L I L I V A C E A Q Q L P R
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q6PEH9 847 95085 V340 S V T V T Q A V E L E T S G D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VSL7 706 77357 R149 G T C V P G S R L V H H V Q P
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q9XTQ7 462 49322 D108 H S H D E E E D H H H G H A H
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9M647 469 50564 L112 F A L W L N A L G C S L L V S
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.2 88.4 72.3 N.A. 83.8 29.2 N.A. 23.7 24.6 N.A. 29.5 N.A. 26.2 N.A. 24.1 N.A.
Protein Similarity: 100 99.4 90.4 74.9 N.A. 87.3 43.7 N.A. 31.5 36.1 N.A. 41.7 N.A. 39.9 N.A. 37.4 N.A.
P-Site Identity: 100 100 13.3 6.6 N.A. 6.6 20 N.A. 0 6.6 N.A. 0 N.A. 6.6 N.A. 0 N.A.
P-Site Similarity: 100 100 33.3 13.3 N.A. 13.3 26.6 N.A. 0 26.6 N.A. 13.3 N.A. 20 N.A. 0 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 20.4 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 35.2 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 20 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 17 17 0 0 9 0 34 0 0 9 9 9 0 9 0 % A
% Cys: 0 0 9 0 0 0 0 9 0 9 0 0 0 0 0 % C
% Asp: 9 9 9 9 0 0 0 9 9 0 0 25 9 0 25 % D
% Glu: 0 0 0 0 17 9 9 0 17 0 17 0 0 17 25 % E
% Phe: 9 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 9 17 9 0 0 25 17 0 34 17 17 25 9 9 0 % G
% His: 9 0 9 9 9 0 0 0 9 9 17 9 17 0 9 % H
% Ile: 0 0 9 0 9 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 17 17 9 25 25 0 9 9 9 0 9 34 9 0 % L
% Met: 0 0 25 9 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 9 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 34 17 0 17 9 0 0 0 0 0 9 17 % P
% Gln: 0 9 0 0 0 9 0 0 9 0 9 9 0 17 0 % Q
% Arg: 0 0 0 0 0 0 0 9 0 0 0 0 0 0 9 % R
% Ser: 34 9 0 0 0 9 17 25 9 9 9 0 9 9 9 % S
% Thr: 0 9 9 0 9 0 0 0 0 0 0 9 9 9 0 % T
% Val: 0 9 0 17 0 9 0 25 0 17 0 0 9 9 0 % V
% Trp: 9 0 0 9 0 0 0 0 0 17 17 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _