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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC39A5
All Species:
17.88
Human Site:
S161
Identified Species:
35.76
UniProt:
Q6ZMH5
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6ZMH5
NP_001128667.1
539
56330
S161
N
E
D
C
L
N
G
S
Q
L
L
V
N
F
G
Chimpanzee
Pan troglodytes
XP_509141
540
56446
S162
N
E
D
C
L
N
G
S
Q
L
L
V
N
F
G
Rhesus Macaque
Macaca mulatta
XP_001114684
546
57047
S168
Q
A
G
C
L
N
G
S
Q
L
L
V
N
F
G
Dog
Lupus familis
XP_538229
449
46237
A150
L
L
L
D
H
S
L
A
D
H
L
N
E
D
C
Cat
Felis silvestris
Mouse
Mus musculus
Q9D856
535
56257
S160
N
E
D
C
L
N
G
S
Q
L
L
V
N
F
G
Rat
Rattus norvegicus
A0JPN2
656
71103
K281
D
T
L
C
L
S
A
K
D
V
M
A
V
Y
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519251
329
34223
F30
L
G
P
G
A
C
L
F
K
I
G
S
R
L
P
Chicken
Gallus gallus
Q5ZI20
366
39255
V67
S
L
I
G
S
F
M
V
G
L
S
G
I
F
P
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q6PEH9
847
95085
T387
H
E
E
C
L
N
L
T
Q
L
L
H
Q
Y
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VSL7
706
77357
N196
I
C
P
S
L
P
N
N
N
T
H
P
L
G
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9XTQ7
462
49322
T155
S
F
L
N
D
A
K
T
R
L
W
V
Y
A
I
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9M647
469
50564
F159
G
A
M
L
G
D
A
F
L
H
Q
L
P
H
A
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
88.4
72.3
N.A.
83.8
29.2
N.A.
23.7
24.6
N.A.
29.5
N.A.
26.2
N.A.
24.1
N.A.
Protein Similarity:
100
99.4
90.4
74.9
N.A.
87.3
43.7
N.A.
31.5
36.1
N.A.
41.7
N.A.
39.9
N.A.
37.4
N.A.
P-Site Identity:
100
100
80
6.6
N.A.
100
20
N.A.
0
13.3
N.A.
53.3
N.A.
6.6
N.A.
13.3
N.A.
P-Site Similarity:
100
100
80
20
N.A.
100
53.3
N.A.
13.3
20
N.A.
80
N.A.
13.3
N.A.
33.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.4
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
35.2
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
17
0
0
9
9
17
9
0
0
0
9
0
9
9
% A
% Cys:
0
9
0
50
0
9
0
0
0
0
0
0
0
0
9
% C
% Asp:
9
0
25
9
9
9
0
0
17
0
0
0
0
9
0
% D
% Glu:
0
34
9
0
0
0
0
0
0
0
0
0
9
0
0
% E
% Phe:
0
9
0
0
0
9
0
17
0
0
0
0
0
42
0
% F
% Gly:
9
9
9
17
9
0
34
0
9
0
9
9
0
9
50
% G
% His:
9
0
0
0
9
0
0
0
0
17
9
9
0
9
0
% H
% Ile:
9
0
9
0
0
0
0
0
0
9
0
0
9
0
9
% I
% Lys:
0
0
0
0
0
0
9
9
9
0
0
0
0
0
9
% K
% Leu:
17
17
25
9
59
0
25
0
9
59
50
9
9
9
0
% L
% Met:
0
0
9
0
0
0
9
0
0
0
9
0
0
0
0
% M
% Asn:
25
0
0
9
0
42
9
9
9
0
0
9
34
0
0
% N
% Pro:
0
0
17
0
0
9
0
0
0
0
0
9
9
0
17
% P
% Gln:
9
0
0
0
0
0
0
0
42
0
9
0
9
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
9
0
0
0
9
0
0
% R
% Ser:
17
0
0
9
9
17
0
34
0
0
9
9
0
0
0
% S
% Thr:
0
9
0
0
0
0
0
17
0
9
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
9
0
9
0
42
9
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
9
17
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _