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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC39A5
All Species:
10.61
Human Site:
S358
Identified Species:
21.21
UniProt:
Q6ZMH5
Number Species:
11
Phosphosite Substitution
Charge Score:
0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6ZMH5
NP_001128667.1
539
56330
S358
Q
G
Q
R
E
K
N
S
Q
H
P
P
A
L
A
Chimpanzee
Pan troglodytes
XP_509141
540
56446
S359
Q
G
Q
R
E
Q
N
S
Q
H
P
P
A
L
A
Rhesus Macaque
Macaca mulatta
XP_001114684
546
57047
S365
Q
G
Q
R
E
Q
N
S
Q
H
P
P
A
P
A
Dog
Lupus familis
XP_538229
449
46237
R285
Q
G
H
S
H
G
S
R
G
G
A
G
A
N
I
Cat
Felis silvestris
Mouse
Mus musculus
Q9D856
535
56257
N354
E
V
Q
G
Q
R
E
N
R
Q
S
S
P
S
L
Rat
Rattus norvegicus
A0JPN2
656
71103
D481
P
H
E
S
S
R
S
D
L
V
T
E
E
T
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519251
329
34223
D165
L
E
P
G
L
S
L
D
V
W
S
G
L
P
T
Chicken
Gallus gallus
Q5ZI20
366
39255
T202
Q
R
A
E
K
N
S
T
Q
C
N
G
S
S
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q6PEH9
847
95085
H663
G
H
G
H
G
H
G
H
G
H
G
H
S
H
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VSL7
706
77357
H519
V
T
V
I
L
R
E
H
E
S
S
H
H
G
H
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9XTQ7
462
49322
E290
G
E
K
K
E
T
K
E
K
D
S
K
D
K
V
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9M647
469
50564
G299
A
T
D
K
S
D
S
G
T
E
I
T
S
D
G
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
88.4
72.3
N.A.
83.8
29.2
N.A.
23.7
24.6
N.A.
29.5
N.A.
26.2
N.A.
24.1
N.A.
Protein Similarity:
100
99.4
90.4
74.9
N.A.
87.3
43.7
N.A.
31.5
36.1
N.A.
41.7
N.A.
39.9
N.A.
37.4
N.A.
P-Site Identity:
100
93.3
86.6
20
N.A.
6.6
0
N.A.
0
13.3
N.A.
6.6
N.A.
0
N.A.
6.6
N.A.
P-Site Similarity:
100
100
93.3
26.6
N.A.
40
20
N.A.
0
40
N.A.
13.3
N.A.
13.3
N.A.
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.4
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
35.2
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
9
0
0
0
0
0
0
0
9
0
34
0
25
% A
% Cys:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% C
% Asp:
0
0
9
0
0
9
0
17
0
9
0
0
9
9
0
% D
% Glu:
9
17
9
9
34
0
17
9
9
9
0
9
9
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
17
34
9
17
9
9
9
9
17
9
9
25
0
9
9
% G
% His:
0
17
9
9
9
9
0
17
0
34
0
17
9
9
17
% H
% Ile:
0
0
0
9
0
0
0
0
0
0
9
0
0
0
9
% I
% Lys:
0
0
9
17
9
9
9
0
9
0
0
9
0
9
0
% K
% Leu:
9
0
0
0
17
0
9
0
9
0
0
0
9
17
17
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
9
25
9
0
0
9
0
0
9
0
% N
% Pro:
9
0
9
0
0
0
0
0
0
0
25
25
9
17
9
% P
% Gln:
42
0
34
0
9
17
0
0
34
9
0
0
0
0
0
% Q
% Arg:
0
9
0
25
0
25
0
9
9
0
0
0
0
0
0
% R
% Ser:
0
0
0
17
17
9
34
25
0
9
34
9
25
17
0
% S
% Thr:
0
17
0
0
0
9
0
9
9
0
9
9
0
9
9
% T
% Val:
9
9
9
0
0
0
0
0
9
9
0
0
0
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _