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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SLC39A5 All Species: 8.79
Human Site: S373 Identified Species: 17.58
UniProt: Q6ZMH5 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6ZMH5 NP_001128667.1 539 56330 S373 P P G H Q G H S H G H Q G G T
Chimpanzee Pan troglodytes XP_509141 540 56446 S374 P P G H Q G H S H G H Q G G A
Rhesus Macaque Macaca mulatta XP_001114684 546 57047 S380 P P G H Q G H S H G H Q G G T
Dog Lupus familis XP_538229 449 46237 D300 T W M V L L G D A L H N L T D
Cat Felis silvestris
Mouse Mus musculus Q9D856 535 56257 H369 A P P G H Q G H S H E H R G G
Rat Rattus norvegicus A0JPN2 656 71103 R496 E L L N P D T R R L R A E L R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519251 329 34223 R180 G P S L W G A R E E P G G P S
Chicken Gallus gallus Q5ZI20 366 39255 R217 Q S C R T D N R I K I S G Y L
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q6PEH9 847 95085 E678 G H C H S D Q E M K D A G I A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VSL7 706 77357 H534 S H R H G H V H S P P E T L S
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q9XTQ7 462 49322 E305 A K K E E K P E K D E Q S I K
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9M647 469 50564 V314 K S D K P E Q V E T R S S S L
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.2 88.4 72.3 N.A. 83.8 29.2 N.A. 23.7 24.6 N.A. 29.5 N.A. 26.2 N.A. 24.1 N.A.
Protein Similarity: 100 99.4 90.4 74.9 N.A. 87.3 43.7 N.A. 31.5 36.1 N.A. 41.7 N.A. 39.9 N.A. 37.4 N.A.
P-Site Identity: 100 93.3 100 6.6 N.A. 13.3 0 N.A. 20 6.6 N.A. 13.3 N.A. 6.6 N.A. 6.6 N.A.
P-Site Similarity: 100 93.3 100 6.6 N.A. 13.3 6.6 N.A. 26.6 13.3 N.A. 13.3 N.A. 20 N.A. 13.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 20.4 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 35.2 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 0 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 0 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 17 0 0 0 0 0 9 0 9 0 0 17 0 0 17 % A
% Cys: 0 0 17 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 9 0 0 25 0 9 0 9 9 0 0 0 9 % D
% Glu: 9 0 0 9 9 9 0 17 17 9 17 9 9 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 17 0 25 9 9 34 17 0 0 25 0 9 50 34 9 % G
% His: 0 17 0 42 9 9 25 17 25 9 34 9 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 9 0 9 0 0 17 0 % I
% Lys: 9 9 9 9 0 9 0 0 9 17 0 0 0 0 9 % K
% Leu: 0 9 9 9 9 9 0 0 0 17 0 0 9 17 17 % L
% Met: 0 0 9 0 0 0 0 0 9 0 0 0 0 0 0 % M
% Asn: 0 0 0 9 0 0 9 0 0 0 0 9 0 0 0 % N
% Pro: 25 42 9 0 17 0 9 0 0 9 17 0 0 9 0 % P
% Gln: 9 0 0 0 25 9 17 0 0 0 0 34 0 0 0 % Q
% Arg: 0 0 9 9 0 0 0 25 9 0 17 0 9 0 9 % R
% Ser: 9 17 9 0 9 0 0 25 17 0 0 17 17 9 17 % S
% Thr: 9 0 0 0 9 0 9 0 0 9 0 0 9 9 17 % T
% Val: 0 0 0 9 0 0 9 9 0 0 0 0 0 0 0 % V
% Trp: 0 9 0 0 9 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _