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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SLC39A5 All Species: 4.55
Human Site: S92 Identified Species: 9.09
UniProt: Q6ZMH5 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6ZMH5 NP_001128667.1 539 56330 S92 A S P A A D N S T H R P Q N P
Chimpanzee Pan troglodytes XP_509141 540 56446 S93 A S P A A D N S T H R P Q N P
Rhesus Macaque Macaca mulatta XP_001114684 546 57047 F99 N S T H R Q G F A M L P R L F
Dog Lupus familis XP_538229 449 46237 A81 L G H H G P P A G R A A P P A
Cat Felis silvestris
Mouse Mus musculus Q9D856 535 56257 N91 A A P T S G D N F T H R L Q E
Rat Rattus norvegicus A0JPN2 656 71103 Q212 F V D F V F R Q L S S K P R N
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519251 329 34223
Chicken Gallus gallus Q5ZI20 366 39255
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q6PEH9 847 95085 R318 A N Q T R R H R R P S K V K A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VSL7 706 77357 L127 S S G F D G L L Q Q L S L H S
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q9XTQ7 462 49322 H86 G H A H D H D H G H A H D H G
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9M647 469 50564 C90 R L C G F G P C L H D H D H E
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.2 88.4 72.3 N.A. 83.8 29.2 N.A. 23.7 24.6 N.A. 29.5 N.A. 26.2 N.A. 24.1 N.A.
Protein Similarity: 100 99.4 90.4 74.9 N.A. 87.3 43.7 N.A. 31.5 36.1 N.A. 41.7 N.A. 39.9 N.A. 37.4 N.A.
P-Site Identity: 100 100 13.3 0 N.A. 13.3 0 N.A. 0 0 N.A. 6.6 N.A. 6.6 N.A. 6.6 N.A.
P-Site Similarity: 100 100 20 6.6 N.A. 40 0 N.A. 0 0 N.A. 20 N.A. 20 N.A. 20 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 20.4 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 35.2 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 34 9 9 17 17 0 0 9 9 0 17 9 0 0 17 % A
% Cys: 0 0 9 0 0 0 0 9 0 0 0 0 0 0 0 % C
% Asp: 0 0 9 0 17 17 17 0 0 0 9 0 17 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 17 % E
% Phe: 9 0 0 17 9 9 0 9 9 0 0 0 0 0 9 % F
% Gly: 9 9 9 9 9 25 9 0 17 0 0 0 0 0 9 % G
% His: 0 9 9 25 0 9 9 9 0 34 9 17 0 25 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 17 0 9 0 % K
% Leu: 9 9 0 0 0 0 9 9 17 0 17 0 17 9 0 % L
% Met: 0 0 0 0 0 0 0 0 0 9 0 0 0 0 0 % M
% Asn: 9 9 0 0 0 0 17 9 0 0 0 0 0 17 9 % N
% Pro: 0 0 25 0 0 9 17 0 0 9 0 25 17 9 17 % P
% Gln: 0 0 9 0 0 9 0 9 9 9 0 0 17 9 0 % Q
% Arg: 9 0 0 0 17 9 9 9 9 9 17 9 9 9 0 % R
% Ser: 9 34 0 0 9 0 0 17 0 9 17 9 0 0 9 % S
% Thr: 0 0 9 17 0 0 0 0 17 9 0 0 0 0 0 % T
% Val: 0 9 0 0 9 0 0 0 0 0 0 0 9 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _