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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
THSD4
All Species:
13.64
Human Site:
S458
Identified Species:
33.33
UniProt:
Q6ZMP0
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6ZMP0
NP_079093.2
1018
112450
S458
Y
L
A
L
R
S
R
S
G
R
S
I
I
N
G
Chimpanzee
Pan troglodytes
XP_523113
1017
112376
S457
Y
L
A
L
R
S
R
S
G
R
S
I
I
N
G
Rhesus Macaque
Macaca mulatta
XP_001089233
695
77390
E178
A
G
E
S
F
L
A
E
G
P
T
N
E
I
L
Dog
Lupus familis
XP_544753
731
81639
G215
G
E
S
F
L
A
E
G
P
T
N
E
I
L
D
Cat
Felis silvestris
Mouse
Mus musculus
Q3UTY6
1018
113224
S458
Y
L
A
L
R
S
R
S
G
R
S
I
I
N
G
Rat
Rattus norvegicus
Q4FZU4
1030
112766
G436
G
R
R
P
D
G
C
G
V
C
G
G
D
G
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_413780
1008
112452
S459
Y
L
A
L
R
S
R
S
G
R
S
I
I
N
G
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_684575
641
70986
P125
G
D
W
V
I
D
R
P
G
Q
F
Y
A
A
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392121
710
77519
N194
E
I
L
A
Q
E
M
N
P
G
V
L
Y
K
Y
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001182864
608
67786
V92
C
G
P
N
T
I
D
V
C
V
D
G
V
C
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
67.5
64.2
N.A.
87.9
39.1
N.A.
N.A.
73.7
N.A.
34.7
N.A.
N.A.
22.2
N.A.
23.4
Protein Similarity:
100
99.5
68
67.4
N.A.
91.8
53.5
N.A.
N.A.
82.9
N.A.
45
N.A.
N.A.
35.4
N.A.
34.3
P-Site Identity:
100
100
6.6
6.6
N.A.
100
0
N.A.
N.A.
100
N.A.
20
N.A.
N.A.
0
N.A.
0
P-Site Similarity:
100
100
13.3
26.6
N.A.
100
0
N.A.
N.A.
100
N.A.
33.3
N.A.
N.A.
26.6
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
40
10
0
10
10
0
0
0
0
0
10
10
0
% A
% Cys:
10
0
0
0
0
0
10
0
10
10
0
0
0
10
0
% C
% Asp:
0
10
0
0
10
10
10
0
0
0
10
0
10
0
10
% D
% Glu:
10
10
10
0
0
10
10
10
0
0
0
10
10
0
0
% E
% Phe:
0
0
0
10
10
0
0
0
0
0
10
0
0
0
0
% F
% Gly:
30
20
0
0
0
10
0
20
60
10
10
20
0
10
50
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
10
0
0
10
10
0
0
0
0
0
40
50
10
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% K
% Leu:
0
40
10
40
10
10
0
0
0
0
0
10
0
10
10
% L
% Met:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
10
0
0
0
10
0
0
10
10
0
40
0
% N
% Pro:
0
0
10
10
0
0
0
10
20
10
0
0
0
0
0
% P
% Gln:
0
0
0
0
10
0
0
0
0
10
0
0
0
0
0
% Q
% Arg:
0
10
10
0
40
0
50
0
0
40
0
0
0
0
10
% R
% Ser:
0
0
10
10
0
40
0
40
0
0
40
0
0
0
10
% S
% Thr:
0
0
0
0
10
0
0
0
0
10
10
0
0
0
0
% T
% Val:
0
0
0
10
0
0
0
10
10
10
10
0
10
0
0
% V
% Trp:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
40
0
0
0
0
0
0
0
0
0
0
10
10
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _