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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
THSD4
All Species:
13.33
Human Site:
S660
Identified Species:
32.59
UniProt:
Q6ZMP0
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6ZMP0
NP_079093.2
1018
112450
S660
A
P
E
S
Y
C
D
S
S
M
K
P
T
P
E
Chimpanzee
Pan troglodytes
XP_523113
1017
112376
S659
A
P
E
S
Y
C
D
S
S
M
K
P
T
P
E
Rhesus Macaque
Macaca mulatta
XP_001089233
695
77390
S363
F
W
D
I
G
E
W
S
E
C
S
K
T
C
G
Dog
Lupus familis
XP_544753
731
81639
E400
W
D
I
G
E
W
S
E
C
S
K
T
C
G
L
Cat
Felis silvestris
Mouse
Mus musculus
Q3UTY6
1018
113224
S660
V
P
E
S
Y
C
D
S
S
M
K
P
T
P
E
Rat
Rattus norvegicus
Q4FZU4
1030
112766
V665
L
D
E
Q
S
C
A
V
G
A
R
P
P
A
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_413780
1008
112452
S650
V
P
E
N
Y
C
D
S
S
T
K
P
I
P
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_684575
641
70986
K310
G
E
W
S
E
C
S
K
T
C
G
P
G
F
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392121
710
77519
L379
T
G
T
R
T
R
K
L
E
C
V
Q
E
L
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001182864
608
67786
V277
G
G
F
Q
T
R
T
V
T
C
T
R
S
G
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
67.5
64.2
N.A.
87.9
39.1
N.A.
N.A.
73.7
N.A.
34.7
N.A.
N.A.
22.2
N.A.
23.4
Protein Similarity:
100
99.5
68
67.4
N.A.
91.8
53.5
N.A.
N.A.
82.9
N.A.
45
N.A.
N.A.
35.4
N.A.
34.3
P-Site Identity:
100
100
13.3
6.6
N.A.
93.3
20
N.A.
N.A.
73.3
N.A.
20
N.A.
N.A.
0
N.A.
0
P-Site Similarity:
100
100
20
6.6
N.A.
93.3
26.6
N.A.
N.A.
80
N.A.
33.3
N.A.
N.A.
6.6
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
20
0
0
0
0
0
10
0
0
10
0
0
0
10
0
% A
% Cys:
0
0
0
0
0
60
0
0
10
40
0
0
10
10
0
% C
% Asp:
0
20
10
0
0
0
40
0
0
0
0
0
0
0
10
% D
% Glu:
0
10
50
0
20
10
0
10
20
0
0
0
10
0
40
% E
% Phe:
10
0
10
0
0
0
0
0
0
0
0
0
0
10
0
% F
% Gly:
20
20
0
10
10
0
0
0
10
0
10
0
10
20
10
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
10
10
0
0
0
0
0
0
0
0
10
0
0
% I
% Lys:
0
0
0
0
0
0
10
10
0
0
50
10
0
0
10
% K
% Leu:
10
0
0
0
0
0
0
10
0
0
0
0
0
10
10
% L
% Met:
0
0
0
0
0
0
0
0
0
30
0
0
0
0
0
% M
% Asn:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
40
0
0
0
0
0
0
0
0
0
60
10
40
0
% P
% Gln:
0
0
0
20
0
0
0
0
0
0
0
10
0
0
10
% Q
% Arg:
0
0
0
10
0
20
0
0
0
0
10
10
0
0
0
% R
% Ser:
0
0
0
40
10
0
20
50
40
10
10
0
10
0
10
% S
% Thr:
10
0
10
0
20
0
10
0
20
10
10
10
40
0
0
% T
% Val:
20
0
0
0
0
0
0
20
0
0
10
0
0
0
0
% V
% Trp:
10
10
10
0
0
10
10
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
40
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _