KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
THSD4
All Species:
15.45
Human Site:
Y511
Identified Species:
37.78
UniProt:
Q6ZMP0
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6ZMP0
NP_079093.2
1018
112450
Y511
T
N
E
I
L
D
V
Y
M
I
H
Q
Q
P
N
Chimpanzee
Pan troglodytes
XP_523113
1017
112376
Y510
T
N
E
I
L
D
V
Y
M
I
H
Q
Q
P
N
Rhesus Macaque
Macaca mulatta
XP_001089233
695
77390
E231
F
N
G
Q
L
V
T
E
G
R
S
Q
E
E
G
Dog
Lupus familis
XP_544753
731
81639
G268
N
G
Q
L
V
T
D
G
R
S
Q
E
E
R
E
Cat
Felis silvestris
Mouse
Mus musculus
Q3UTY6
1018
113224
Y511
T
N
E
I
L
D
V
Y
M
I
H
Q
Q
P
N
Rat
Rattus norvegicus
Q4FZU4
1030
112766
R489
S
S
N
Y
L
A
L
R
G
P
G
G
R
S
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_413780
1008
112452
Y512
T
N
E
V
L
D
V
Y
M
I
H
Q
Q
P
N
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_684575
641
70986
Y178
D
A
A
V
Y
Y
E
Y
I
L
P
K
H
T
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392121
710
77519
K247
V
N
R
I
S
N
Q
K
I
D
L
L
P
A
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001182864
608
67786
I145
L
P
E
G
Y
N
D
I
H
I
I
P
A
G
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
67.5
64.2
N.A.
87.9
39.1
N.A.
N.A.
73.7
N.A.
34.7
N.A.
N.A.
22.2
N.A.
23.4
Protein Similarity:
100
99.5
68
67.4
N.A.
91.8
53.5
N.A.
N.A.
82.9
N.A.
45
N.A.
N.A.
35.4
N.A.
34.3
P-Site Identity:
100
100
20
0
N.A.
100
6.6
N.A.
N.A.
93.3
N.A.
13.3
N.A.
N.A.
13.3
N.A.
13.3
P-Site Similarity:
100
100
26.6
33.3
N.A.
100
33.3
N.A.
N.A.
100
N.A.
40
N.A.
N.A.
26.6
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
10
0
0
10
0
0
0
0
0
0
10
10
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
0
0
0
40
20
0
0
10
0
0
0
0
0
% D
% Glu:
0
0
50
0
0
0
10
10
0
0
0
10
20
10
10
% E
% Phe:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
10
10
10
0
0
0
10
20
0
10
10
0
10
10
% G
% His:
0
0
0
0
0
0
0
0
10
0
40
0
10
0
0
% H
% Ile:
0
0
0
40
0
0
0
10
20
50
10
0
0
0
20
% I
% Lys:
0
0
0
0
0
0
0
10
0
0
0
10
0
0
0
% K
% Leu:
10
0
0
10
60
0
10
0
0
10
10
10
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
40
0
0
0
0
0
0
% M
% Asn:
10
60
10
0
0
20
0
0
0
0
0
0
0
0
50
% N
% Pro:
0
10
0
0
0
0
0
0
0
10
10
10
10
40
0
% P
% Gln:
0
0
10
10
0
0
10
0
0
0
10
50
40
0
0
% Q
% Arg:
0
0
10
0
0
0
0
10
10
10
0
0
10
10
0
% R
% Ser:
10
10
0
0
10
0
0
0
0
10
10
0
0
10
0
% S
% Thr:
40
0
0
0
0
10
10
0
0
0
0
0
0
10
0
% T
% Val:
10
0
0
20
10
10
40
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
10
20
10
0
50
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _