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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
THSD4
All Species:
12.42
Human Site:
Y525
Identified Species:
30.37
UniProt:
Q6ZMP0
Number Species:
9
Phosphosite Substitution
Charge Score:
0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6ZMP0
NP_079093.2
1018
112450
Y525
N
P
G
V
H
Y
E
Y
V
I
M
G
T
N
A
Chimpanzee
Pan troglodytes
XP_523113
1017
112376
Y524
N
P
G
V
H
Y
E
Y
V
I
M
G
T
N
A
Rhesus Macaque
Macaca mulatta
XP_001089233
695
77390
E245
G
E
E
K
G
R
N
E
E
K
E
D
L
R
G
Dog
Lupus familis
XP_544753
731
81639
E282
E
D
K
E
E
T
E
E
K
E
D
V
R
G
G
Cat
Felis silvestris
Mouse
Mus musculus
Q3UTY6
1018
113224
Y525
N
P
G
V
H
Y
E
Y
V
I
M
R
N
N
A
Rat
Rattus norvegicus
Q4FZU4
1030
112766
V503
I
I
N
G
N
W
A
V
D
P
P
G
S
Y
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_413780
1008
112452
Y526
N
P
G
I
H
Y
E
Y
I
I
P
G
D
N
V
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_684575
641
70986
S192
N
T
H
S
D
A
Y
S
Y
S
S
V
L
P
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392121
710
77519
R261
I
R
N
Q
D
R
A
R
G
R
E
R
G
R
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001182864
608
67786
E159
A
T
N
G
R
I
A
E
I
R
G
S
H
N
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
67.5
64.2
N.A.
87.9
39.1
N.A.
N.A.
73.7
N.A.
34.7
N.A.
N.A.
22.2
N.A.
23.4
Protein Similarity:
100
99.5
68
67.4
N.A.
91.8
53.5
N.A.
N.A.
82.9
N.A.
45
N.A.
N.A.
35.4
N.A.
34.3
P-Site Identity:
100
100
0
6.6
N.A.
86.6
13.3
N.A.
N.A.
66.6
N.A.
6.6
N.A.
N.A.
0
N.A.
6.6
P-Site Similarity:
100
100
0
6.6
N.A.
86.6
33.3
N.A.
N.A.
80
N.A.
6.6
N.A.
N.A.
0
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
0
10
30
0
0
0
0
0
0
0
40
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
0
0
20
0
0
0
10
0
10
10
10
0
0
% D
% Glu:
10
10
10
10
10
0
50
30
10
10
20
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
10
0
40
20
10
0
0
0
10
0
10
40
10
10
20
% G
% His:
0
0
10
0
40
0
0
0
0
0
0
0
10
0
0
% H
% Ile:
20
10
0
10
0
10
0
0
20
40
0
0
0
0
0
% I
% Lys:
0
0
10
10
0
0
0
0
10
10
0
0
0
0
10
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
20
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
30
0
0
0
0
% M
% Asn:
50
0
30
0
10
0
10
0
0
0
0
0
10
50
0
% N
% Pro:
0
40
0
0
0
0
0
0
0
10
20
0
0
10
0
% P
% Gln:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
10
0
0
10
20
0
10
0
20
0
20
10
20
0
% R
% Ser:
0
0
0
10
0
0
0
10
0
10
10
10
10
0
0
% S
% Thr:
0
20
0
0
0
10
0
0
0
0
0
0
20
0
0
% T
% Val:
0
0
0
30
0
0
0
10
30
0
0
20
0
0
10
% V
% Trp:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
40
10
40
10
0
0
0
0
10
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _