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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
JHDM1D
All Species:
23.33
Human Site:
S665
Identified Species:
46.67
UniProt:
Q6ZMT4
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6ZMT4
NP_085150.1
941
106557
S665
D
I
S
E
S
E
D
S
G
P
E
C
T
A
L
Chimpanzee
Pan troglodytes
XP_527907
941
106392
S665
D
I
S
E
S
E
D
S
G
P
E
C
T
A
L
Rhesus Macaque
Macaca mulatta
XP_001109325
941
106786
S665
D
I
S
E
S
E
D
S
G
P
E
C
T
A
L
Dog
Lupus familis
XP_539885
1083
121420
S806
D
I
S
D
S
E
D
S
G
P
D
C
T
A
L
Cat
Felis silvestris
Mouse
Mus musculus
Q3UWM4
940
106057
S665
D
G
S
D
S
E
D
S
G
P
D
C
T
A
L
Rat
Rattus norvegicus
XP_001069774
798
90335
I536
P
D
C
T
A
L
K
I
N
F
A
T
E
E
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508061
901
102658
S624
S
T
E
E
S
E
S
S
G
D
E
E
K
Q
E
Chicken
Gallus gallus
XP_416344
962
109181
S684
D
I
S
D
S
E
E
S
E
P
D
C
T
T
Q
Frog
Xenopus laevis
NP_001085579
419
48261
G157
D
V
E
R
Y
V
G
G
E
K
I
V
D
V
I
Zebra Danio
Brachydanio rerio
XP_686713
577
66988
L315
V
R
Q
G
T
T
L
L
I
P
T
G
W
I
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_394272
917
104227
K653
D
V
L
N
D
V
P
K
N
G
I
E
E
L
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_789776
951
107984
L677
L
S
N
V
D
V
L
L
Q
A
T
K
L
E
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
97.7
78.8
N.A.
90.2
74.1
N.A.
74.3
77.1
38.8
43.6
N.A.
N.A.
34.5
N.A.
33.9
Protein Similarity:
100
99.4
98.5
81.9
N.A.
94.5
78.4
N.A.
82
85.5
42.2
51.6
N.A.
N.A.
52.5
N.A.
53.5
P-Site Identity:
100
100
100
86.6
N.A.
80
0
N.A.
40
60
6.6
6.6
N.A.
N.A.
13.3
N.A.
0
P-Site Similarity:
100
100
100
100
N.A.
93.3
6.6
N.A.
40
80
20
13.3
N.A.
N.A.
20
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
9
0
0
0
0
9
9
0
0
42
0
% A
% Cys:
0
0
9
0
0
0
0
0
0
0
0
50
0
0
0
% C
% Asp:
67
9
0
25
17
0
42
0
0
9
25
0
9
0
0
% D
% Glu:
0
0
17
34
0
59
9
0
17
0
34
17
17
17
9
% E
% Phe:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% F
% Gly:
0
9
0
9
0
0
9
9
50
9
0
9
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% H
% Ile:
0
42
0
0
0
0
0
9
9
0
17
0
0
9
9
% I
% Lys:
0
0
0
0
0
0
9
9
0
9
0
9
9
0
0
% K
% Leu:
9
0
9
0
0
9
17
17
0
0
0
0
9
9
50
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
9
9
0
0
0
0
17
0
0
0
0
0
0
% N
% Pro:
9
0
0
0
0
0
9
0
0
59
0
0
0
0
9
% P
% Gln:
0
0
9
0
0
0
0
0
9
0
0
0
0
9
9
% Q
% Arg:
0
9
0
9
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
9
9
50
0
59
0
9
59
0
0
0
0
0
0
9
% S
% Thr:
0
9
0
9
9
9
0
0
0
0
17
9
50
9
0
% T
% Val:
9
17
0
9
0
25
0
0
0
0
0
9
0
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% W
% Tyr:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _