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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
JHDM1D
All Species:
18.18
Human Site:
Y600
Identified Species:
36.36
UniProt:
Q6ZMT4
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6ZMT4
NP_085150.1
941
106557
Y600
P
F
A
D
Q
S
L
Y
T
A
D
S
E
N
E
Chimpanzee
Pan troglodytes
XP_527907
941
106392
Y600
P
F
A
D
Q
S
L
Y
T
A
D
S
E
N
E
Rhesus Macaque
Macaca mulatta
XP_001109325
941
106786
Y600
P
F
A
D
Q
S
L
Y
T
A
D
S
E
N
E
Dog
Lupus familis
XP_539885
1083
121420
Y741
P
F
A
D
P
S
L
Y
T
A
D
S
E
N
E
Cat
Felis silvestris
Mouse
Mus musculus
Q3UWM4
940
106057
Y600
L
F
A
D
R
S
L
Y
T
A
D
S
E
N
E
Rat
Rattus norvegicus
XP_001069774
798
90335
D471
A
D
S
E
N
E
E
D
K
K
P
T
K
K
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508061
901
102658
K559
S
K
K
P
K
K
V
K
I
E
Q
N
S
G
L
Chicken
Gallus gallus
XP_416344
962
109181
T619
F
T
D
R
S
L
Y
T
A
D
S
E
D
E
D
Frog
Xenopus laevis
NP_001085579
419
48261
I92
Q
A
G
T
R
T
F
I
Q
A
L
R
A
R
S
Zebra Danio
Brachydanio rerio
XP_686713
577
66988
H250
K
D
S
Y
T
D
F
H
I
D
F
G
G
T
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_394272
917
104227
H588
N
E
F
S
S
D
H
H
L
G
T
A
K
E
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_789776
951
107984
D612
V
D
D
I
S
A
E
D
I
K
E
R
R
K
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
97.7
78.8
N.A.
90.2
74.1
N.A.
74.3
77.1
38.8
43.6
N.A.
N.A.
34.5
N.A.
33.9
Protein Similarity:
100
99.4
98.5
81.9
N.A.
94.5
78.4
N.A.
82
85.5
42.2
51.6
N.A.
N.A.
52.5
N.A.
53.5
P-Site Identity:
100
100
100
93.3
N.A.
86.6
0
N.A.
0
0
6.6
0
N.A.
N.A.
0
N.A.
0
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
26.6
N.A.
20
13.3
20
13.3
N.A.
N.A.
20
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
9
42
0
0
9
0
0
9
50
0
9
9
0
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
25
17
42
0
17
0
17
0
17
42
0
9
0
9
% D
% Glu:
0
9
0
9
0
9
17
0
0
9
9
9
42
17
42
% E
% Phe:
9
42
9
0
0
0
17
0
0
0
9
0
0
0
0
% F
% Gly:
0
0
9
0
0
0
0
0
0
9
0
9
9
9
0
% G
% His:
0
0
0
0
0
0
9
17
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
9
0
0
0
9
25
0
0
0
0
0
0
% I
% Lys:
9
9
9
0
9
9
0
9
9
17
0
0
17
17
0
% K
% Leu:
9
0
0
0
0
9
42
0
9
0
9
0
0
0
25
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
9
0
0
0
9
0
0
0
0
0
0
9
0
42
0
% N
% Pro:
34
0
0
9
9
0
0
0
0
0
9
0
0
0
0
% P
% Gln:
9
0
0
0
25
0
0
0
9
0
9
0
0
0
0
% Q
% Arg:
0
0
0
9
17
0
0
0
0
0
0
17
9
9
0
% R
% Ser:
9
0
17
9
25
42
0
0
0
0
9
42
9
0
17
% S
% Thr:
0
9
0
9
9
9
0
9
42
0
9
9
0
9
0
% T
% Val:
9
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
9
0
0
9
42
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _