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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SMEK3P
All Species:
18.79
Human Site:
T452
Identified Species:
41.33
UniProt:
Q6ZMV5
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6ZMV5
NP_001116436
832
95776
T452
L
D
P
R
N
M
L
T
T
P
E
K
S
E
R
Chimpanzee
Pan troglodytes
XP_528914
832
95829
T452
L
D
P
R
N
M
L
T
T
P
E
K
S
E
R
Rhesus Macaque
Macaca mulatta
XP_001092955
823
94860
T451
L
D
P
R
N
M
L
T
T
P
E
K
S
E
R
Dog
Lupus familis
XP_548911
1123
126649
T792
L
D
P
E
N
M
L
T
T
S
N
K
C
E
R
Cat
Felis silvestris
Mouse
Mus musculus
Q922R5
820
93916
T453
D
P
E
N
M
L
A
T
T
N
K
T
E
K
S
Rat
Rattus norvegicus
NP_001101837
820
93952
T453
D
P
E
N
M
L
A
T
T
N
K
T
E
K
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510357
821
93689
T454
D
P
E
N
M
L
A
T
A
N
K
T
E
K
S
Chicken
Gallus gallus
XP_424305
819
93429
A451
I
D
P
E
N
M
L
A
T
A
N
K
T
E
K
Frog
Xenopus laevis
Q7ZX60
820
93708
A452
I
D
P
E
N
M
L
A
T
A
N
K
T
E
K
Zebra Danio
Brachydanio rerio
Q5SP90
818
93771
A450
V
D
P
E
N
M
L
A
T
A
N
K
T
E
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VFS5
980
109277
T479
V
A
P
V
I
L
N
T
I
G
D
R
P
Q
N
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.3
90.6
46
N.A.
59.1
59.2
N.A.
56.7
58
58.8
50.8
N.A.
38.8
N.A.
N.A.
N.A.
Protein Similarity:
100
99
93.9
56.4
N.A.
74.5
74.6
N.A.
72
73.3
73.6
68.8
N.A.
57.9
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
73.3
N.A.
13.3
13.3
N.A.
6.6
53.3
53.3
53.3
N.A.
13.3
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
73.3
N.A.
33.3
33.3
N.A.
26.6
73.3
73.3
73.3
N.A.
46.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
0
0
28
28
10
28
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% C
% Asp:
28
64
0
0
0
0
0
0
0
0
10
0
0
0
0
% D
% Glu:
0
0
28
37
0
0
0
0
0
0
28
0
28
64
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
19
0
0
0
10
0
0
0
10
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
28
64
0
28
28
% K
% Leu:
37
0
0
0
0
37
64
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
28
64
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
28
64
0
10
0
0
28
37
0
0
0
10
% N
% Pro:
0
28
73
0
0
0
0
0
0
28
0
0
10
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% Q
% Arg:
0
0
0
28
0
0
0
0
0
0
0
10
0
0
37
% R
% Ser:
0
0
0
0
0
0
0
0
0
10
0
0
28
0
28
% S
% Thr:
0
0
0
0
0
0
0
73
82
0
0
28
28
0
0
% T
% Val:
19
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _