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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KIF6 All Species: 16.67
Human Site: S288 Identified Species: 30.56
UniProt: Q6ZMV9 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6ZMV9 NP_659464.3 814 92569 S288 E Q V I I A L S E K H R S H I
Chimpanzee Pan troglodytes XP_518451 814 92867 S288 E Q V I I A L S E K H R S H I
Rhesus Macaque Macaca mulatta XP_001117160 818 92984 S288 E Q V I I A L S E K H R S H I
Dog Lupus familis XP_538903 838 94815 S288 E Q V I I A L S E K H R A H I
Cat Felis silvestris
Mouse Mus musculus Q9WV04 790 89924 G283 E Q A I I A L G D Q N R D H V
Rat Rattus norvegicus Q7TSP2 1385 159522 T300 S C L G Q V I T A L V D V G N
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis Q91785 1388 159123 A307 I T A L V D V A N G R Q R H I
Zebra Danio Brachydanio rerio NP_001070899 667 75528 D247 C S K L H L V D L A G S E R V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_394791 753 86748 G294 E Q V I V C L G Q E S M G H I
Nematode Worm Caenorhab. elegans P46873 699 78760 P278 D G K S K H I P Y R D S K L T
Sea Urchin Strong. purpuratus P46872 699 78679 N279 L S L S T L G N V I S S L V D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9FZ06 919 100869 S346 K S I N L S L S A L G K C I N
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa P48467 928 102392 H279 L T D G K S S H V P Y R D S K
Conservation
Percent
Protein Identity: 100 97.4 96.6 78.8 N.A. 27.7 20.7 N.A. N.A. N.A. 21.9 50.3 N.A. N.A. 35.1 26 27.2
Protein Similarity: 100 98.6 97.4 83.8 N.A. 49 36 N.A. N.A. N.A. 36.8 63.7 N.A. N.A. 53 46.1 46.1
P-Site Identity: 100 100 100 93.3 N.A. 53.3 0 N.A. N.A. N.A. 13.3 0 N.A. N.A. 46.6 0 0
P-Site Similarity: 100 100 100 100 N.A. 80 20 N.A. N.A. N.A. 46.6 20 N.A. N.A. 66.6 20 13.3
Percent
Protein Identity: N.A. N.A. N.A. 23.5 N.A. 24.3
Protein Similarity: N.A. N.A. N.A. 42 N.A. 44.2
P-Site Identity: N.A. N.A. N.A. 13.3 N.A. 6.6
P-Site Similarity: N.A. N.A. N.A. 46.6 N.A. 20
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 16 0 0 39 0 8 16 8 0 0 8 0 0 % A
% Cys: 8 8 0 0 0 8 0 0 0 0 0 0 8 0 0 % C
% Asp: 8 0 8 0 0 8 0 8 8 0 8 8 16 0 8 % D
% Glu: 47 0 0 0 0 0 0 0 31 8 0 0 8 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 8 0 16 0 0 8 16 0 8 16 0 8 8 0 % G
% His: 0 0 0 0 8 8 0 8 0 0 31 0 0 54 0 % H
% Ile: 8 0 8 47 39 0 16 0 0 8 0 0 0 8 47 % I
% Lys: 8 0 16 0 16 0 0 0 0 31 0 8 8 0 8 % K
% Leu: 16 0 16 16 8 16 54 0 8 16 0 0 8 8 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % M
% Asn: 0 0 0 8 0 0 0 8 8 0 8 0 0 0 16 % N
% Pro: 0 0 0 0 0 0 0 8 0 8 0 0 0 0 0 % P
% Gln: 0 47 0 0 8 0 0 0 8 8 0 8 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 8 8 47 8 8 0 % R
% Ser: 8 24 0 16 0 16 8 39 0 0 16 24 24 8 0 % S
% Thr: 0 16 0 0 8 0 0 8 0 0 0 0 0 0 8 % T
% Val: 0 0 39 0 16 8 16 0 16 0 8 0 8 8 16 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 8 0 8 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _