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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KIF6 All Species: 15.45
Human Site: S323 Identified Species: 28.33
UniProt: Q6ZMV9 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.17
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6ZMV9 NP_659464.3 814 92569 S323 T T M I A T L S L E K R N L D
Chimpanzee Pan troglodytes XP_518451 814 92867 S323 T T M I A T L S L E K R N L D
Rhesus Macaque Macaca mulatta XP_001117160 818 92984 S323 T T M I A T L S L E K R N L D
Dog Lupus familis XP_538903 838 94815 S323 T T M I A T L S L E K R N I D
Cat Felis silvestris
Mouse Mus musculus Q9WV04 790 89924 Y318 M V L V T N I Y G E A A Q L D
Rat Rattus norvegicus Q7TSP2 1385 159522 A335 L G G N A K T A I I A N V H P
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis Q91785 1388 159123 H342 T F Y I A N V H P G S K C F G
Zebra Danio Brachydanio rerio NP_001070899 667 75528 I282 H Y L E Q V I I A L S E K D R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_394791 753 86748 N329 T A M L A T L N I T S F N L E
Nematode Worm Caenorhab. elegans P46873 699 78760 E313 P S S D N Y D E T L S T L R Y
Sea Urchin Strong. purpuratus P46872 699 78679 V314 L G G N A K T V M C A N I G P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9FZ06 919 100869 A381 R D S F G G T A R T S L V I T
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa P48467 928 102392 D314 C S P S S Y N D A E T L S T L
Conservation
Percent
Protein Identity: 100 97.4 96.6 78.8 N.A. 27.7 20.7 N.A. N.A. N.A. 21.9 50.3 N.A. N.A. 35.1 26 27.2
Protein Similarity: 100 98.6 97.4 83.8 N.A. 49 36 N.A. N.A. N.A. 36.8 63.7 N.A. N.A. 53 46.1 46.1
P-Site Identity: 100 100 100 93.3 N.A. 20 6.6 N.A. N.A. N.A. 20 0 N.A. N.A. 46.6 0 6.6
P-Site Similarity: 100 100 100 100 N.A. 40 20 N.A. N.A. N.A. 33.3 13.3 N.A. N.A. 73.3 6.6 13.3
Percent
Protein Identity: N.A. N.A. N.A. 23.5 N.A. 24.3
Protein Similarity: N.A. N.A. N.A. 42 N.A. 44.2
P-Site Identity: N.A. N.A. N.A. 0 N.A. 6.6
P-Site Similarity: N.A. N.A. N.A. 13.3 N.A. 26.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 0 0 62 0 0 16 16 0 24 8 0 0 0 % A
% Cys: 8 0 0 0 0 0 0 0 0 8 0 0 8 0 0 % C
% Asp: 0 8 0 8 0 0 8 8 0 0 0 0 0 8 39 % D
% Glu: 0 0 0 8 0 0 0 8 0 47 0 8 0 0 8 % E
% Phe: 0 8 0 8 0 0 0 0 0 0 0 8 0 8 0 % F
% Gly: 0 16 16 0 8 8 0 0 8 8 0 0 0 8 8 % G
% His: 8 0 0 0 0 0 0 8 0 0 0 0 0 8 0 % H
% Ile: 0 0 0 39 0 0 16 8 16 8 0 0 8 16 0 % I
% Lys: 0 0 0 0 0 16 0 0 0 0 31 8 8 0 0 % K
% Leu: 16 0 16 8 0 0 39 0 31 16 0 16 8 39 8 % L
% Met: 8 0 39 0 0 0 0 0 8 0 0 0 0 0 0 % M
% Asn: 0 0 0 16 8 16 8 8 0 0 0 16 39 0 0 % N
% Pro: 8 0 8 0 0 0 0 0 8 0 0 0 0 0 16 % P
% Gln: 0 0 0 0 8 0 0 0 0 0 0 0 8 0 0 % Q
% Arg: 8 0 0 0 0 0 0 0 8 0 0 31 0 8 8 % R
% Ser: 0 16 16 8 8 0 0 31 0 0 39 0 8 0 0 % S
% Thr: 47 31 0 0 8 39 24 0 8 16 8 8 0 8 8 % T
% Val: 0 8 0 8 0 8 8 8 0 0 0 0 16 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 8 8 0 0 16 0 8 0 0 0 0 0 0 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _