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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KIF6 All Species: 14.24
Human Site: S401 Identified Species: 26.11
UniProt: Q6ZMV9 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6ZMV9 NP_659464.3 814 92569 S401 Q L E K L I T S F L E D Q D S
Chimpanzee Pan troglodytes XP_518451 814 92867 S401 Q L E K L I T S F L E D Q D P
Rhesus Macaque Macaca mulatta XP_001117160 818 92984 S401 Q L E K L I T S F L E D Q D P
Dog Lupus familis XP_538903 838 94815 S401 Q L E K L I T S F L D D Q D P
Cat Felis silvestris
Mouse Mus musculus Q9WV04 790 89924 R379 I H D S L S N R T L V N Y D P
Rat Rattus norvegicus Q7TSP2 1385 159522 L445 K I T Q L E D L T L K K E K F
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis Q91785 1388 159123 K453 Q L E D L C N K K E K F I Q S
Zebra Danio Brachydanio rerio NP_001070899 667 75528 L331 K N I G E S L L K A R V R E K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_394791 753 86748 A383 R L K Q Q I K A L T M Q T N E
Nematode Worm Caenorhab. elegans P46873 699 78760 V363 V Q P G A V G V G A P A Q D A
Sea Urchin Strong. purpuratus P46872 699 78679 E363 L L R E F Q K E I E E L K K Q
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9FZ06 919 100869 V433 S L S R R L E V Q L D N L I E
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa P48467 928 102392 T393 P P L E L A I T P S K S A S T
Conservation
Percent
Protein Identity: 100 97.4 96.6 78.8 N.A. 27.7 20.7 N.A. N.A. N.A. 21.9 50.3 N.A. N.A. 35.1 26 27.2
Protein Similarity: 100 98.6 97.4 83.8 N.A. 49 36 N.A. N.A. N.A. 36.8 63.7 N.A. N.A. 53 46.1 46.1
P-Site Identity: 100 93.3 93.3 86.6 N.A. 20 13.3 N.A. N.A. N.A. 33.3 0 N.A. N.A. 13.3 13.3 13.3
P-Site Similarity: 100 93.3 93.3 93.3 N.A. 33.3 46.6 N.A. N.A. N.A. 40 20 N.A. N.A. 46.6 26.6 26.6
Percent
Protein Identity: N.A. N.A. N.A. 23.5 N.A. 24.3
Protein Similarity: N.A. N.A. N.A. 42 N.A. 44.2
P-Site Identity: N.A. N.A. N.A. 13.3 N.A. 6.6
P-Site Similarity: N.A. N.A. N.A. 40 N.A. 33.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 8 8 0 8 0 16 0 8 8 0 8 % A
% Cys: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 8 8 0 0 8 0 0 0 16 31 0 47 0 % D
% Glu: 0 0 39 16 8 8 8 8 0 16 31 0 8 8 16 % E
% Phe: 0 0 0 0 8 0 0 0 31 0 0 8 0 0 8 % F
% Gly: 0 0 0 16 0 0 8 0 8 0 0 0 0 0 0 % G
% His: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 8 8 8 0 0 39 8 0 8 0 0 0 8 8 0 % I
% Lys: 16 0 8 31 0 0 16 8 16 0 24 8 8 16 8 % K
% Leu: 8 62 8 0 62 8 8 16 8 54 0 8 8 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % M
% Asn: 0 8 0 0 0 0 16 0 0 0 0 16 0 8 0 % N
% Pro: 8 8 8 0 0 0 0 0 8 0 8 0 0 0 31 % P
% Gln: 39 8 0 16 8 8 0 0 8 0 0 8 39 8 8 % Q
% Arg: 8 0 8 8 8 0 0 8 0 0 8 0 8 0 0 % R
% Ser: 8 0 8 8 0 16 0 31 0 8 0 8 0 8 16 % S
% Thr: 0 0 8 0 0 0 31 8 16 8 0 0 8 0 8 % T
% Val: 8 0 0 0 0 8 0 16 0 0 8 8 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _