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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KIF6 All Species: 14.85
Human Site: S506 Identified Species: 27.22
UniProt: Q6ZMV9 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6ZMV9 NP_659464.3 814 92569 S506 D R R E F R Q S Q S P P F R L
Chimpanzee Pan troglodytes XP_518451 814 92867 S506 D R R E F R H S Q S P P F R L
Rhesus Macaque Macaca mulatta XP_001117160 818 92984 S510 D R R E F R H S Q S P P F P P
Dog Lupus familis XP_538903 838 94815 S506 D R S E C R H S Q S L P F P P
Cat Felis silvestris
Mouse Mus musculus Q9WV04 790 89924 I447 L R R K Y T L I D K N D F A A
Rat Rattus norvegicus Q7TSP2 1385 159522 T661 E T L K I I T T P T K A Y Q L
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis Q91785 1388 159123 N795 L E K Q K Q E N K S Q E D V L
Zebra Danio Brachydanio rerio NP_001070899 667 75528 K389 M L K R E K K K L Q D V T S Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_394791 753 86748 I461 V V Q R D K E I S L L I D K L
Nematode Worm Caenorhab. elegans P46873 699 78760 A421 A D Y E R A N A N L D N L N P
Sea Urchin Strong. purpuratus P46872 699 78679 Q421 P E I M A A M Q K K I D E E K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9FZ06 919 100869 N496 S I K K L E E N W S K N Q K K
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa P48467 928 102392 T468 A E R Q L R E T K E E L I A L
Conservation
Percent
Protein Identity: 100 97.4 96.6 78.8 N.A. 27.7 20.7 N.A. N.A. N.A. 21.9 50.3 N.A. N.A. 35.1 26 27.2
Protein Similarity: 100 98.6 97.4 83.8 N.A. 49 36 N.A. N.A. N.A. 36.8 63.7 N.A. N.A. 53 46.1 46.1
P-Site Identity: 100 93.3 80 60 N.A. 20 6.6 N.A. N.A. N.A. 13.3 0 N.A. N.A. 6.6 6.6 0
P-Site Similarity: 100 93.3 80 60 N.A. 33.3 46.6 N.A. N.A. N.A. 53.3 20 N.A. N.A. 33.3 13.3 6.6
Percent
Protein Identity: N.A. N.A. N.A. 23.5 N.A. 24.3
Protein Similarity: N.A. N.A. N.A. 42 N.A. 44.2
P-Site Identity: N.A. N.A. N.A. 6.6 N.A. 20
P-Site Similarity: N.A. N.A. N.A. 40 N.A. 46.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 16 0 0 0 8 16 0 8 0 0 0 8 0 16 8 % A
% Cys: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 31 8 0 0 8 0 0 0 8 0 16 16 16 0 0 % D
% Glu: 8 24 0 39 8 8 31 0 0 8 8 8 8 8 0 % E
% Phe: 0 0 0 0 24 0 0 0 0 0 0 0 39 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 24 0 0 0 0 0 0 0 0 % H
% Ile: 0 8 8 0 8 8 0 16 0 0 8 8 8 0 0 % I
% Lys: 0 0 24 24 8 16 8 8 24 16 16 0 0 16 16 % K
% Leu: 16 8 8 0 16 0 8 0 8 16 16 8 8 0 47 % L
% Met: 8 0 0 8 0 0 8 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 8 16 8 0 8 16 0 8 0 % N
% Pro: 8 0 0 0 0 0 0 0 8 0 24 31 0 16 24 % P
% Gln: 0 0 8 16 0 8 8 8 31 8 8 0 8 8 8 % Q
% Arg: 0 39 39 16 8 39 0 0 0 0 0 0 0 16 0 % R
% Ser: 8 0 8 0 0 0 0 31 8 47 0 0 0 8 0 % S
% Thr: 0 8 0 0 0 8 8 16 0 8 0 0 8 0 0 % T
% Val: 8 8 0 0 0 0 0 0 0 0 0 8 0 8 0 % V
% Trp: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % W
% Tyr: 0 0 8 0 8 0 0 0 0 0 0 0 8 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _