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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KIF6 All Species: 14.85
Human Site: S525 Identified Species: 27.22
UniProt: Q6ZMV9 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.33
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6ZMV9 NP_659464.3 814 92569 S525 E G Q R M R L S S A P S Q A Q
Chimpanzee Pan troglodytes XP_518451 814 92867 S525 E G Q R M R L S S A P S Q A Q
Rhesus Macaque Macaca mulatta XP_001117160 818 92984 S529 E G Q R M R L S S A P S Q A Q
Dog Lupus familis XP_538903 838 94815 S524 E G L R T L P S S A P K Q I Q
Cat Felis silvestris
Mouse Mus musculus Q9WV04 790 89924 E467 K V G L M D I E G N L V G E P
Rat Rattus norvegicus Q7TSP2 1385 159522 Q708 V P P E M S E Q A L E A I S E
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis Q91785 1388 159123 E890 E I D Q L K Q E I S D S K H E
Zebra Danio Brachydanio rerio NP_001070899 667 75528 S406 K P Q N K N E S P T T L E A A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_394791 753 86748 T478 K E R S T L D T S G N D F S I
Nematode Worm Caenorhab. elegans P46873 699 78760 L438 A A K K I Q Q L Q D Q F I G G
Sea Urchin Strong. purpuratus P46872 699 78679 V438 L E E K K D M V E E D R N T V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9FZ06 919 100869 D518 L G E K N G L D I T S N G N R
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa P48467 928 102392 E506 Q L E R L A F E N K E A Q I T
Conservation
Percent
Protein Identity: 100 97.4 96.6 78.8 N.A. 27.7 20.7 N.A. N.A. N.A. 21.9 50.3 N.A. N.A. 35.1 26 27.2
Protein Similarity: 100 98.6 97.4 83.8 N.A. 49 36 N.A. N.A. N.A. 36.8 63.7 N.A. N.A. 53 46.1 46.1
P-Site Identity: 100 100 100 60 N.A. 6.6 6.6 N.A. N.A. N.A. 13.3 20 N.A. N.A. 6.6 0 0
P-Site Similarity: 100 100 100 60 N.A. 20 33.3 N.A. N.A. N.A. 53.3 33.3 N.A. N.A. 33.3 26.6 20
Percent
Protein Identity: N.A. N.A. N.A. 23.5 N.A. 24.3
Protein Similarity: N.A. N.A. N.A. 42 N.A. 44.2
P-Site Identity: N.A. N.A. N.A. 13.3 N.A. 13.3
P-Site Similarity: N.A. N.A. N.A. 40 N.A. 46.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 8 0 0 0 8 0 0 8 31 0 16 0 31 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 8 0 0 16 8 8 0 8 16 8 0 0 0 % D
% Glu: 39 16 24 8 0 0 16 24 8 8 16 0 8 8 16 % E
% Phe: 0 0 0 0 0 0 8 0 0 0 0 8 8 0 0 % F
% Gly: 0 39 8 0 0 8 0 0 8 8 0 0 16 8 8 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % H
% Ile: 0 8 0 0 8 0 8 0 16 0 0 0 16 16 8 % I
% Lys: 24 0 8 24 16 8 0 0 0 8 0 8 8 0 0 % K
% Leu: 16 8 8 8 16 16 31 8 0 8 8 8 0 0 0 % L
% Met: 0 0 0 0 39 0 8 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 8 8 8 0 0 8 8 8 8 8 8 0 % N
% Pro: 0 16 8 0 0 0 8 0 8 0 31 0 0 0 8 % P
% Gln: 8 0 31 8 0 8 16 8 8 0 8 0 39 0 31 % Q
% Arg: 0 0 8 39 0 24 0 0 0 0 0 8 0 0 8 % R
% Ser: 0 0 0 8 0 8 0 39 39 8 8 31 0 16 0 % S
% Thr: 0 0 0 0 16 0 0 8 0 16 8 0 0 8 8 % T
% Val: 8 8 0 0 0 0 0 8 0 0 0 8 0 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _