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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KIF6 All Species: 13.64
Human Site: S774 Identified Species: 25
UniProt: Q6ZMV9 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6ZMV9 NP_659464.3 814 92569 S774 T S T P L E D S I P K R P V S
Chimpanzee Pan troglodytes XP_518451 814 92867 S774 T S T P L E D S I P K R P V S
Rhesus Macaque Macaca mulatta XP_001117160 818 92984 S778 T S T P L E D S I P K R P T S
Dog Lupus familis XP_538903 838 94815 S754 T S A S L E S S V P E R P A S
Cat Felis silvestris
Mouse Mus musculus Q9WV04 790 89924 E741 S R I V C L G E D D Q D R F S
Rat Rattus norvegicus Q7TSP2 1385 159522 D1222 L L Q T Q L D D M K R Q G E S
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis Q91785 1388 159123 E1243 D M Q D L K R E I E K E V S E
Zebra Danio Brachydanio rerio NP_001070899 667 75528 S628 R D K R S L P S C D F S S T P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_394791 753 86748 K713 K A E R F D Q K S D L G E E S
Nematode Worm Caenorhab. elegans P46873 699 78760 F660 L S T S K S L F P S K T P T F
Sea Urchin Strong. purpuratus P46872 699 78679 G660 T Y N L E G G G M K Y K P S Q
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9FZ06 919 100869 S829 Q G T K R G K S L L I E D G A
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa P48467 928 102392 K786 N N R A Q Q K K M A F L E R N
Conservation
Percent
Protein Identity: 100 97.4 96.6 78.8 N.A. 27.7 20.7 N.A. N.A. N.A. 21.9 50.3 N.A. N.A. 35.1 26 27.2
Protein Similarity: 100 98.6 97.4 83.8 N.A. 49 36 N.A. N.A. N.A. 36.8 63.7 N.A. N.A. 53 46.1 46.1
P-Site Identity: 100 100 93.3 60 N.A. 6.6 13.3 N.A. N.A. N.A. 20 6.6 N.A. N.A. 6.6 26.6 13.3
P-Site Similarity: 100 100 93.3 73.3 N.A. 20 33.3 N.A. N.A. N.A. 26.6 6.6 N.A. N.A. 20 26.6 26.6
Percent
Protein Identity: N.A. N.A. N.A. 23.5 N.A. 24.3
Protein Similarity: N.A. N.A. N.A. 42 N.A. 44.2
P-Site Identity: N.A. N.A. N.A. 13.3 N.A. 0
P-Site Similarity: N.A. N.A. N.A. 26.6 N.A. 26.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 8 8 0 0 0 0 0 8 0 0 0 8 8 % A
% Cys: 0 0 0 0 8 0 0 0 8 0 0 0 0 0 0 % C
% Asp: 8 8 0 8 0 8 31 8 8 24 0 8 8 0 0 % D
% Glu: 0 0 8 0 8 31 0 16 0 8 8 16 16 16 8 % E
% Phe: 0 0 0 0 8 0 0 8 0 0 16 0 0 8 8 % F
% Gly: 0 8 0 0 0 16 16 8 0 0 0 8 8 8 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 8 0 0 0 0 0 31 0 8 0 0 0 0 % I
% Lys: 8 0 8 8 8 8 16 16 0 16 39 8 0 0 0 % K
% Leu: 16 8 0 8 39 24 8 0 8 8 8 8 0 0 0 % L
% Met: 0 8 0 0 0 0 0 0 24 0 0 0 0 0 0 % M
% Asn: 8 8 8 0 0 0 0 0 0 0 0 0 0 0 8 % N
% Pro: 0 0 0 24 0 0 8 0 8 31 0 0 47 0 8 % P
% Gln: 8 0 16 0 16 8 8 0 0 0 8 8 0 0 8 % Q
% Arg: 8 8 8 16 8 0 8 0 0 0 8 31 8 8 0 % R
% Ser: 8 39 0 16 8 8 8 47 8 8 0 8 8 16 54 % S
% Thr: 39 0 39 8 0 0 0 0 0 0 0 8 0 24 0 % T
% Val: 0 0 0 8 0 0 0 0 8 0 0 0 8 16 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 8 0 0 0 0 0 0 0 0 8 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _