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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KIF6 All Species: 14.24
Human Site: T140 Identified Species: 26.11
UniProt: Q6ZMV9 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6ZMV9 NP_659464.3 814 92569 T140 K D S S K I Y T T H I S Y L E
Chimpanzee Pan troglodytes XP_518451 814 92867 T140 K D S S K I Y T T H I S Y L E
Rhesus Macaque Macaca mulatta XP_001117160 818 92984 T140 K D S S K M Y T T H I S Y L E
Dog Lupus familis XP_538903 838 94815 T140 K D S S T I H T T H I S Y L E
Cat Felis silvestris
Mouse Mus musculus Q9WV04 790 89924 I135 E E R P T H A I T V R V S Y L
Rat Rattus norvegicus Q7TSP2 1385 159522 E152 S L I D R E K E K A G A G K S
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis Q91785 1388 159123 K159 K E K A G E G K S F L C K C S
Zebra Danio Brachydanio rerio NP_001070899 667 75528 G99 A Y G Q T G S G K T F T I T G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_394791 753 86748 A146 N V Y S I E V A Y L E I Y N E
Nematode Worm Caenorhab. elegans P46873 699 78760 L130 T T E N V K F L V H C S Y L E
Sea Urchin Strong. purpuratus P46872 699 78679 I131 F A H I F G H I A K E Q E N V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9FZ06 919 100869 S198 S L E T D S I S V S Y L Q L Y
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa P48467 928 102392 E131 L S S A A N I E Y T V R V S Y
Conservation
Percent
Protein Identity: 100 97.4 96.6 78.8 N.A. 27.7 20.7 N.A. N.A. N.A. 21.9 50.3 N.A. N.A. 35.1 26 27.2
Protein Similarity: 100 98.6 97.4 83.8 N.A. 49 36 N.A. N.A. N.A. 36.8 63.7 N.A. N.A. 53 46.1 46.1
P-Site Identity: 100 100 93.3 86.6 N.A. 6.6 0 N.A. N.A. N.A. 6.6 0 N.A. N.A. 20 33.3 0
P-Site Similarity: 100 100 100 93.3 N.A. 20 13.3 N.A. N.A. N.A. 33.3 6.6 N.A. N.A. 20 46.6 6.6
Percent
Protein Identity: N.A. N.A. N.A. 23.5 N.A. 24.3
Protein Similarity: N.A. N.A. N.A. 42 N.A. 44.2
P-Site Identity: N.A. N.A. N.A. 6.6 N.A. 6.6
P-Site Similarity: N.A. N.A. N.A. 20 N.A. 20
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 8 0 16 8 0 8 8 8 8 0 8 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 8 8 0 8 0 % C
% Asp: 0 31 0 8 8 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 8 16 16 0 0 24 0 16 0 0 16 0 8 0 47 % E
% Phe: 8 0 0 0 8 0 8 0 0 8 8 0 0 0 0 % F
% Gly: 0 0 8 0 8 16 8 8 0 0 8 0 8 0 8 % G
% His: 0 0 8 0 0 8 16 0 0 39 0 0 0 0 0 % H
% Ile: 0 0 8 8 8 24 16 16 0 0 31 8 8 0 0 % I
% Lys: 39 0 8 0 24 8 8 8 16 8 0 0 8 8 0 % K
% Leu: 8 16 0 0 0 0 0 8 0 8 8 8 0 47 8 % L
% Met: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % M
% Asn: 8 0 0 8 0 8 0 0 0 0 0 0 0 16 0 % N
% Pro: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 8 0 0 0 0 0 0 0 8 8 0 0 % Q
% Arg: 0 0 8 0 8 0 0 0 0 0 8 8 0 0 0 % R
% Ser: 16 8 39 39 0 8 8 8 8 8 0 39 8 8 16 % S
% Thr: 8 8 0 8 24 0 0 31 39 16 0 8 0 8 0 % T
% Val: 0 8 0 0 8 0 8 0 16 8 8 8 8 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 8 8 0 0 0 24 0 16 0 8 0 47 8 16 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _