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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RNF19B All Species: 12.73
Human Site: S537 Identified Species: 28
UniProt: Q6ZMZ0 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.2
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6ZMZ0 NP_001120833.1 732 77925 S537 S S G K G K Y S R L E V Q A D
Chimpanzee Pan troglodytes XP_524554 639 68865 L446 G K G K Y S R L E V Q A D V Q
Rhesus Macaque Macaca mulatta XP_001099161 525 56557 V342 M L A Y V Y G V V P I S L C R
Dog Lupus familis XP_535322 544 57853 K361 V Q K E I F P K D T A S L G A
Cat Felis silvestris
Mouse Mus musculus A2A7Q9 732 78109 S534 S S G K G K Y S R L E V Q A D
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508674 806 85935 S610 S G G K G K Y S R L E V H A D
Chicken Gallus gallus XP_417816 706 75747 S500 S G G K G K Y S R L E V Q A D
Frog Xenopus laevis Q08B84 687 74523 G501 L A G G T L T G G M L S G G R
Zebra Danio Brachydanio rerio Q1L8L6 701 74925 R518 A R T G K Y S R L E V Q G T E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_623728 825 90208 Q592 S S V L P G G Q R L E V Q A D
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_780939 783 83193 G501 L S G S G G V G P L V L N S H
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 87 70.9 72.6 N.A. 94.4 N.A. N.A. 64.8 81.1 66.1 59.9 N.A. N.A. 39.5 N.A. 41.5
Protein Similarity: 100 87.1 71.3 73 N.A. 95.7 N.A. N.A. 69.8 84.6 74.4 69.5 N.A. N.A. 53.7 N.A. 57.2
P-Site Identity: 100 13.3 0 0 N.A. 100 N.A. N.A. 86.6 93.3 6.6 0 N.A. N.A. 60 N.A. 26.6
P-Site Similarity: 100 26.6 0 6.6 N.A. 100 N.A. N.A. 86.6 93.3 20 13.3 N.A. N.A. 60 N.A. 40
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 10 10 0 0 0 0 0 0 0 10 10 0 46 10 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % C
% Asp: 0 0 0 0 0 0 0 0 10 0 0 0 10 0 46 % D
% Glu: 0 0 0 10 0 0 0 0 10 10 46 0 0 0 10 % E
% Phe: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % F
% Gly: 10 19 64 19 46 19 19 19 10 0 0 0 19 19 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 10 % H
% Ile: 0 0 0 0 10 0 0 0 0 0 10 0 0 0 0 % I
% Lys: 0 10 10 46 10 37 0 10 0 0 0 0 0 0 0 % K
% Leu: 19 10 0 10 0 10 0 10 10 55 10 10 19 0 0 % L
% Met: 10 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % N
% Pro: 0 0 0 0 10 0 10 0 10 10 0 0 0 0 0 % P
% Gln: 0 10 0 0 0 0 0 10 0 0 10 10 37 0 10 % Q
% Arg: 0 10 0 0 0 0 10 10 46 0 0 0 0 0 19 % R
% Ser: 46 37 0 10 0 10 10 37 0 0 0 28 0 10 0 % S
% Thr: 0 0 10 0 10 0 10 0 0 10 0 0 0 10 0 % T
% Val: 10 0 10 0 10 0 10 10 10 10 19 46 0 10 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 10 10 19 37 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _