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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RNF19B All Species: 19.09
Human Site: T450 Identified Species: 42
UniProt: Q6ZMZ0 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6ZMZ0 NP_001120833.1 732 77925 T450 G G G C G V S T A N G K G V K
Chimpanzee Pan troglodytes XP_524554 639 68865 K361 G V S T A N G K G V K I E F D
Rhesus Macaque Macaca mulatta XP_001099161 525 56557 L258 K K K I L W Q L G T L I G A P
Dog Lupus familis XP_535322 544 57853 T277 D E D D G P I T V A D A W R A
Cat Felis silvestris
Mouse Mus musculus A2A7Q9 732 78109 T447 G G G C G V S T A N G K G V K
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508674 806 85935 T523 G G G C G V S T A N G K G V K
Chicken Gallus gallus XP_417816 706 75747 T402 G G G C G V S T A N G K G V K
Frog Xenopus laevis Q08B84 687 74523 C417 G V V P V S L C R G G G C G V
Zebra Danio Brachydanio rerio Q1L8L6 701 74925 V434 C R G G G C G V S R G K G R G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_623728 825 90208 T503 S G G C G V S T N G T G V R F
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_780939 783 83193 T415 S G G C G V I T G Y S G G V R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 87 70.9 72.6 N.A. 94.4 N.A. N.A. 64.8 81.1 66.1 59.9 N.A. N.A. 39.5 N.A. 41.5
Protein Similarity: 100 87.1 71.3 73 N.A. 95.7 N.A. N.A. 69.8 84.6 74.4 69.5 N.A. N.A. 53.7 N.A. 57.2
P-Site Identity: 100 6.6 6.6 13.3 N.A. 100 N.A. N.A. 100 100 13.3 33.3 N.A. N.A. 46.6 N.A. 53.3
P-Site Similarity: 100 6.6 6.6 13.3 N.A. 100 N.A. N.A. 100 100 13.3 40 N.A. N.A. 46.6 N.A. 60
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 10 0 0 0 37 10 0 10 0 10 10 % A
% Cys: 10 0 0 55 0 10 0 10 0 0 0 0 10 0 0 % C
% Asp: 10 0 10 10 0 0 0 0 0 0 10 0 0 0 10 % D
% Glu: 0 10 0 0 0 0 0 0 0 0 0 0 10 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 10 % F
% Gly: 55 55 64 10 73 0 19 0 28 19 55 28 64 10 10 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 10 0 0 19 0 0 0 0 19 0 0 0 % I
% Lys: 10 10 10 0 0 0 0 10 0 0 10 46 0 0 37 % K
% Leu: 0 0 0 0 10 0 10 10 0 0 10 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 10 0 0 10 37 0 0 0 0 0 % N
% Pro: 0 0 0 10 0 10 0 0 0 0 0 0 0 0 10 % P
% Gln: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % Q
% Arg: 0 10 0 0 0 0 0 0 10 10 0 0 0 28 10 % R
% Ser: 19 0 10 0 0 10 46 0 10 0 10 0 0 0 0 % S
% Thr: 0 0 0 10 0 0 0 64 0 10 10 0 0 0 0 % T
% Val: 0 19 10 0 10 55 0 10 10 10 0 0 10 46 10 % V
% Trp: 0 0 0 0 0 10 0 0 0 0 0 0 10 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _