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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MEX3B
All Species:
18.18
Human Site:
S140
Identified Species:
40
UniProt:
Q6ZN04
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6ZN04
NP_115622.2
569
58832
S140
H
F
S
M
I
R
A
S
R
N
K
N
T
A
L
Chimpanzee
Pan troglodytes
XP_523137
572
58958
S143
H
F
S
M
I
R
A
S
R
N
K
N
T
A
L
Rhesus Macaque
Macaca mulatta
XP_001110186
570
58837
S142
H
F
S
M
I
R
A
S
R
N
K
N
T
A
L
Dog
Lupus familis
XP_545877
678
69549
D196
Q
L
S
L
L
G
L
D
S
D
E
G
A
S
L
Cat
Felis silvestris
Mouse
Mus musculus
Q69Z36
601
61763
S172
H
F
S
M
I
R
A
S
R
N
K
N
T
A
L
Rat
Rattus norvegicus
XP_001068105
576
59203
S147
H
F
S
M
I
R
A
S
R
N
K
N
T
A
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515618
613
64857
G145
L
D
Q
L
S
I
L
G
L
E
E
E
E
E
M
Chicken
Gallus gallus
XP_418202
443
47323
R45
T
Y
I
K
T
P
V
R
G
E
E
P
I
F
I
Frog
Xenopus laevis
A1L3F4
507
54145
R109
P
V
F
V
V
T
G
R
K
E
D
V
A
L
A
Zebra Danio
Brachydanio rerio
NP_001074462
537
57239
N134
S
M
I
R
A
S
R
N
K
N
S
S
L
N
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_623265
425
43895
L27
S
L
E
D
Q
R
A
L
Q
L
A
L
E
L
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
98.9
76.4
N.A.
92.5
96.3
N.A.
50.5
48.5
72.9
70.4
N.A.
N.A.
44.8
N.A.
N.A.
Protein Similarity:
100
99.1
99.3
76.6
N.A.
92.6
96.5
N.A.
60
58
79.4
77.8
N.A.
N.A.
52.9
N.A.
N.A.
P-Site Identity:
100
100
100
13.3
N.A.
100
100
N.A.
0
0
0
6.6
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
100
100
100
46.6
N.A.
100
100
N.A.
20
20
20
26.6
N.A.
N.A.
20
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
10
0
55
0
0
0
10
0
19
46
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
0
10
0
0
0
10
0
10
10
0
0
0
0
% D
% Glu:
0
0
10
0
0
0
0
0
0
28
28
10
19
10
0
% E
% Phe:
0
46
10
0
0
0
0
0
0
0
0
0
0
10
0
% F
% Gly:
0
0
0
0
0
10
10
10
10
0
0
10
0
0
10
% G
% His:
46
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
19
0
46
10
0
0
0
0
0
0
10
0
10
% I
% Lys:
0
0
0
10
0
0
0
0
19
0
46
0
0
0
0
% K
% Leu:
10
19
0
19
10
0
19
10
10
10
0
10
10
19
55
% L
% Met:
0
10
0
46
0
0
0
0
0
0
0
0
0
0
10
% M
% Asn:
0
0
0
0
0
0
0
10
0
55
0
46
0
10
0
% N
% Pro:
10
0
0
0
0
10
0
0
0
0
0
10
0
0
0
% P
% Gln:
10
0
10
0
10
0
0
0
10
0
0
0
0
0
0
% Q
% Arg:
0
0
0
10
0
55
10
19
46
0
0
0
0
0
0
% R
% Ser:
19
0
55
0
10
10
0
46
10
0
10
10
0
10
10
% S
% Thr:
10
0
0
0
10
10
0
0
0
0
0
0
46
0
0
% T
% Val:
0
10
0
10
10
0
10
0
0
0
0
10
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _