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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MAP3K15
All Species:
0.91
Human Site:
S984
Identified Species:
2.5
UniProt:
Q6ZN16
Number Species:
8
Phosphosite Substitution
Charge Score:
0.38
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6ZN16
NP_001001671.2
1313
147437
S984
L
S
V
P
D
E
S
S
A
L
E
D
R
G
L
Chimpanzee
Pan troglodytes
XP_001171211
1375
154924
E1024
L
F
L
G
I
P
D
E
N
F
E
D
H
S
A
Rhesus Macaque
Macaca mulatta
XP_001111127
1297
143635
V974
G
G
I
S
Q
L
R
V
P
E
E
P
A
A
E
Dog
Lupus familis
XP_548885
1422
158482
L1073
Q
H
Q
L
G
H
L
L
S
V
P
D
E
S
A
Cat
Felis silvestris
Mouse
Mus musculus
A2AQW0
1331
149309
P990
L
S
V
P
D
E
S
P
A
L
D
D
R
S
T
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514080
1407
157705
L1063
L
S
A
P
D
E
S
L
A
S
E
D
R
G
A
Chicken
Gallus gallus
XP_419725
1260
143069
E909
L
F
L
S
I
P
D
E
N
F
E
D
H
S
A
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001155222
1364
153160
E1014
L
F
L
S
I
P
V
E
N
F
E
D
H
S
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001202919
1288
145042
S916
E
L
L
S
P
G
S
S
E
D
G
L
E
T
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
58
44.2
81.6
N.A.
86
N.A.
N.A.
70.8
57.3
N.A.
54.4
N.A.
N.A.
N.A.
N.A.
45.4
Protein Similarity:
100
72.6
60.9
86.4
N.A.
90.3
N.A.
N.A.
79.4
73.5
N.A.
71.5
N.A.
N.A.
N.A.
N.A.
62.2
P-Site Identity:
100
20
6.6
6.6
N.A.
73.3
N.A.
N.A.
73.3
20
N.A.
20
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
26.6
13.3
20
N.A.
80
N.A.
N.A.
73.3
26.6
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
12
0
0
0
0
0
34
0
0
0
12
12
56
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
34
0
23
0
0
12
12
78
0
0
0
% D
% Glu:
12
0
0
0
0
34
0
34
12
12
67
0
23
0
12
% E
% Phe:
0
34
0
0
0
0
0
0
0
34
0
0
0
0
0
% F
% Gly:
12
12
0
12
12
12
0
0
0
0
12
0
0
23
0
% G
% His:
0
12
0
0
0
12
0
0
0
0
0
0
34
0
0
% H
% Ile:
0
0
12
0
34
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
67
12
45
12
0
12
12
23
0
23
0
12
0
0
12
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
34
0
0
0
0
0
0
% N
% Pro:
0
0
0
34
12
34
0
12
12
0
12
12
0
0
12
% P
% Gln:
12
0
12
0
12
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
12
0
0
0
0
0
34
0
0
% R
% Ser:
0
34
0
45
0
0
45
23
12
12
0
0
0
56
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
12
12
% T
% Val:
0
0
23
0
0
0
12
12
0
12
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _