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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DEF8
All Species:
9.09
Human Site:
S292
Identified Species:
15.38
UniProt:
Q6ZN54
Number Species:
13
Phosphosite Substitution
Charge Score:
0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6ZN54
NP_060172.1
512
58710
S292
I
S
L
R
G
V
P
S
E
A
R
Q
C
D
Y
Chimpanzee
Pan troglodytes
XP_523472
386
44371
K216
S
K
P
C
V
S
S
K
V
S
H
Q
A
E
Y
Rhesus Macaque
Macaca mulatta
XP_001092097
445
51385
Q241
R
Q
C
D
Y
T
G
Q
Y
Y
C
S
H
C
H
Dog
Lupus familis
XP_546771
474
55061
S254
I
S
L
R
G
V
P
S
E
A
R
Q
C
D
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q99J78
448
52292
S242
Y
T
G
Q
Y
Y
C
S
H
C
H
W
N
D
L
Rat
Rattus norvegicus
Q4V8I4
451
52679
Q241
R
Q
C
D
Y
T
G
Q
Y
Y
C
S
H
C
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510872
428
48058
E252
Q
H
F
V
E
N
D
E
M
Y
S
L
Q
D
L
Chicken
Gallus gallus
XP_001232734
209
24170
C39
V
K
Q
M
C
D
K
C
S
T
I
I
W
G
L
Frog
Xenopus laevis
Q6DDJ3
443
51304
I241
Y
T
G
Q
Y
Y
C
I
S
C
H
W
N
D
L
Zebra Danio
Brachydanio rerio
NP_001007396
286
33384
E116
H
L
R
L
K
L
Q
E
L
Q
D
P
E
E
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VTT9
492
55389
I256
L
N
I
K
N
T
W
I
E
P
R
L
C
D
Y
Honey Bee
Apis mellifera
XP_393689
483
55355
I247
I
T
F
K
S
A
W
I
E
P
R
L
C
D
Y
Nematode Worm
Caenorhab. elegans
O01738
486
56489
E255
I
C
F
D
G
V
A
E
Q
E
A
R
L
C
D
Sea Urchin
Strong. purpuratus
XP_781480
596
67870
T409
L
A
F
N
G
V
P
T
E
P
R
L
C
D
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
57
83.5
85.7
N.A.
82
81.8
N.A.
38.2
35.5
71
40.2
N.A.
32.8
33.4
31.2
38.9
Protein Similarity:
100
61.5
84.5
87.6
N.A.
84.1
84.5
N.A.
50.9
38.6
77.9
48.2
N.A.
50.3
51.9
46.2
55.3
P-Site Identity:
100
13.3
0
100
N.A.
13.3
0
N.A.
6.6
0
6.6
0
N.A.
33.3
40
20
53.3
P-Site Similarity:
100
26.6
6.6
100
N.A.
26.6
6.6
N.A.
6.6
6.6
20
13.3
N.A.
60
53.3
33.3
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
0
8
8
0
0
15
8
0
8
0
0
% A
% Cys:
0
8
15
8
8
0
15
8
0
15
15
0
36
22
0
% C
% Asp:
0
0
0
22
0
8
8
0
0
0
8
0
0
58
15
% D
% Glu:
0
0
0
0
8
0
0
22
36
8
0
0
8
15
0
% E
% Phe:
0
0
29
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
15
0
29
0
15
0
0
0
0
0
0
8
0
% G
% His:
8
8
0
0
0
0
0
0
8
0
22
0
15
0
15
% H
% Ile:
29
0
8
0
0
0
0
22
0
0
8
8
0
0
0
% I
% Lys:
0
15
0
15
8
0
8
8
0
0
0
0
0
0
0
% K
% Leu:
15
8
15
8
0
8
0
0
8
0
0
29
8
0
29
% L
% Met:
0
0
0
8
0
0
0
0
8
0
0
0
0
0
0
% M
% Asn:
0
8
0
8
8
8
0
0
0
0
0
0
15
0
0
% N
% Pro:
0
0
8
0
0
0
22
0
0
22
0
8
0
0
0
% P
% Gln:
8
15
8
15
0
0
8
15
8
8
0
22
8
0
0
% Q
% Arg:
15
0
8
15
0
0
0
0
0
0
36
8
0
0
0
% R
% Ser:
8
15
0
0
8
8
8
22
15
8
8
15
0
0
0
% S
% Thr:
0
22
0
0
0
22
0
8
0
8
0
0
0
0
0
% T
% Val:
8
0
0
8
8
29
0
0
8
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
15
0
0
0
0
15
8
0
0
% W
% Tyr:
15
0
0
0
29
15
0
0
15
22
0
0
0
0
43
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _