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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DEF8
All Species:
4.85
Human Site:
T25
Identified Species:
8.21
UniProt:
Q6ZN54
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6ZN54
NP_060172.1
512
58710
T25
W
A
D
R
T
L
L
T
P
H
T
G
V
T
S
Chimpanzee
Pan troglodytes
XP_523472
386
44371
Rhesus Macaque
Macaca mulatta
XP_001092097
445
51385
G23
N
P
F
N
K
Q
S
G
P
R
Q
H
E
Q
G
Dog
Lupus familis
XP_546771
474
55061
M24
A
A
V
R
W
D
A
M
E
Y
D
E
K
L
A
Cat
Felis silvestris
Mouse
Mus musculus
Q99J78
448
52292
P24
P
F
N
K
Q
L
G
P
R
H
H
E
Q
E
P
Rat
Rattus norvegicus
Q4V8I4
451
52679
P24
P
F
N
K
H
L
G
P
R
H
H
E
Q
E
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510872
428
48058
E23
P
A
G
R
T
A
M
E
Y
D
E
K
L
A
R
Chicken
Gallus gallus
XP_001232734
209
24170
Frog
Xenopus laevis
Q6DDJ3
443
51304
G23
N
P
F
D
K
Q
G
G
A
E
R
H
P
A
D
Zebra Danio
Brachydanio rerio
NP_001007396
286
33384
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VTT9
492
55389
S30
A
S
N
L
L
H
A
S
S
T
L
G
S
T
V
Honey Bee
Apis mellifera
XP_393689
483
55355
T24
E
I
L
E
T
F
N
T
K
N
N
A
N
G
T
Nematode Worm
Caenorhab. elegans
O01738
486
56489
L27
R
S
R
K
S
S
W
L
I
S
K
I
D
E
N
Sea Urchin
Strong. purpuratus
XP_781480
596
67870
T43
D
S
E
D
E
E
D
T
P
H
S
R
T
S
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
57
83.5
85.7
N.A.
82
81.8
N.A.
38.2
35.5
71
40.2
N.A.
32.8
33.4
31.2
38.9
Protein Similarity:
100
61.5
84.5
87.6
N.A.
84.1
84.5
N.A.
50.9
38.6
77.9
48.2
N.A.
50.3
51.9
46.2
55.3
P-Site Identity:
100
0
6.6
13.3
N.A.
13.3
13.3
N.A.
20
0
0
0
N.A.
13.3
13.3
0
20
P-Site Similarity:
100
0
6.6
26.6
N.A.
26.6
26.6
N.A.
33.3
0
0
0
N.A.
33.3
26.6
26.6
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
15
22
0
0
0
8
15
0
8
0
0
8
0
15
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
8
15
0
8
8
0
0
8
8
0
8
0
8
% D
% Glu:
8
0
8
8
8
8
0
8
8
8
8
22
8
22
0
% E
% Phe:
0
15
15
0
0
8
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
8
0
0
0
22
15
0
0
0
15
0
8
8
% G
% His:
0
0
0
0
8
8
0
0
0
29
15
15
0
0
0
% H
% Ile:
0
8
0
0
0
0
0
0
8
0
0
8
0
0
0
% I
% Lys:
0
0
0
22
15
0
0
0
8
0
8
8
8
0
0
% K
% Leu:
0
0
8
8
8
22
8
8
0
0
8
0
8
8
0
% L
% Met:
0
0
0
0
0
0
8
8
0
0
0
0
0
0
0
% M
% Asn:
15
0
22
8
0
0
8
0
0
8
8
0
8
0
8
% N
% Pro:
22
15
0
0
0
0
0
15
22
0
0
0
8
0
22
% P
% Gln:
0
0
0
0
8
15
0
0
0
0
8
0
15
8
0
% Q
% Arg:
8
0
8
22
0
0
0
0
15
8
8
8
0
0
8
% R
% Ser:
0
22
0
0
8
8
8
8
8
8
8
0
8
8
8
% S
% Thr:
0
0
0
0
22
0
0
22
0
8
8
0
8
15
8
% T
% Val:
0
0
8
0
0
0
0
0
0
0
0
0
8
0
8
% V
% Trp:
8
0
0
0
8
0
8
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
8
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _