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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FRRS1 All Species: 5.76
Human Site: S218 Identified Species: 12.67
UniProt: Q6ZNA5 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6ZNA5 NP_001013682.2 592 66114 S218 C D P E K E A S C V F L S F T
Chimpanzee Pan troglodytes XP_524776 626 70452 S218 C D P E K E A S C V F L S F T
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_547265 591 65769 A218 C D P E K E H A C F F L S F A
Cat Felis silvestris
Mouse Mus musculus Q8K385 592 66029 A218 C D P E K E P A C V F L S F T
Rat Rattus norvegicus XP_001073918 589 65616 A215 C D P E N E P A C V F L S F T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510371 481 54061 S137 G Y L S F A L S H D Q W M G D
Chicken Gallus gallus
Frog Xenopus laevis Q6INU7 590 66105 E217 C D P E H N P E C F F L S F R
Zebra Danio Brachydanio rerio A4QP81 573 61266 Y215 P T T S T G C Y F V A V Q A S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q8MSU3 647 70266 K233 Y N G C G Q S K N C F G F P D
Honey Bee Apis mellifera XP_396579 603 66861 A209 E E K N C I A A V T V L V H G
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_795375 461 49530 V117 P N P Q E G V V K F T L W G T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 86.9 N.A. 83.6 N.A. 78.7 74.4 N.A. 62.5 N.A. 59.6 33.6 N.A. 27.3 27.8 N.A. 24.4
Protein Similarity: 100 89.7 N.A. 91 N.A. 86.9 84.2 N.A. 70 N.A. 75.3 51.5 N.A. 47.2 47.4 N.A. 39.3
P-Site Identity: 100 100 N.A. 73.3 N.A. 86.6 80 N.A. 6.6 N.A. 60 6.6 N.A. 6.6 13.3 N.A. 20
P-Site Similarity: 100 100 N.A. 80 N.A. 93.3 86.6 N.A. 6.6 N.A. 60 20 N.A. 26.6 26.6 N.A. 40
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 10 28 37 0 0 10 0 0 10 10 % A
% Cys: 55 0 0 10 10 0 10 0 55 10 0 0 0 0 0 % C
% Asp: 0 55 0 0 0 0 0 0 0 10 0 0 0 0 19 % D
% Glu: 10 10 0 55 10 46 0 10 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 10 0 0 0 10 28 64 0 10 55 0 % F
% Gly: 10 0 10 0 10 19 0 0 0 0 0 10 0 19 10 % G
% His: 0 0 0 0 10 0 10 0 10 0 0 0 0 10 0 % H
% Ile: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 10 0 37 0 0 10 10 0 0 0 0 0 0 % K
% Leu: 0 0 10 0 0 0 10 0 0 0 0 73 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % M
% Asn: 0 19 0 10 10 10 0 0 10 0 0 0 0 0 0 % N
% Pro: 19 0 64 0 0 0 28 0 0 0 0 0 0 10 0 % P
% Gln: 0 0 0 10 0 10 0 0 0 0 10 0 10 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % R
% Ser: 0 0 0 19 0 0 10 28 0 0 0 0 55 0 10 % S
% Thr: 0 10 10 0 10 0 0 0 0 10 10 0 0 0 46 % T
% Val: 0 0 0 0 0 0 10 10 10 46 10 10 10 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 10 10 0 0 % W
% Tyr: 10 10 0 0 0 0 0 10 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _