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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FRRS1 All Species: 19.39
Human Site: S223 Identified Species: 42.67
UniProt: Q6ZNA5 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6ZNA5 NP_001013682.2 592 66114 S223 E A S C V F L S F T R D D Q S
Chimpanzee Pan troglodytes XP_524776 626 70452 S223 E A S C V F L S F T R D D Q S
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_547265 591 65769 S223 E H A C F F L S F A R D D Q S
Cat Felis silvestris
Mouse Mus musculus Q8K385 592 66029 S223 E P A C V F L S F T R D N Q S
Rat Rattus norvegicus XP_001073918 589 65616 S220 E P A C V F L S F T R E N Q S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510371 481 54061 M142 A L S H D Q W M G D D D A Y L
Chicken Gallus gallus
Frog Xenopus laevis Q6INU7 590 66105 S222 N P E C F F L S F R K D G Q S
Zebra Danio Brachydanio rerio A4QP81 573 61266 Q220 G C Y F V A V Q A S S D Q S E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q8MSU3 647 70266 F238 Q S K N C F G F P D G C V A T
Honey Bee Apis mellifera XP_396579 603 66861 V214 I A A V T V L V H G E R Y L F
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_795375 461 49530 W122 G V V K F T L W G T K V A D Q
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 86.9 N.A. 83.6 N.A. 78.7 74.4 N.A. 62.5 N.A. 59.6 33.6 N.A. 27.3 27.8 N.A. 24.4
Protein Similarity: 100 89.7 N.A. 91 N.A. 86.9 84.2 N.A. 70 N.A. 75.3 51.5 N.A. 47.2 47.4 N.A. 39.3
P-Site Identity: 100 100 N.A. 73.3 N.A. 80 73.3 N.A. 13.3 N.A. 53.3 13.3 N.A. 6.6 13.3 N.A. 13.3
P-Site Similarity: 100 100 N.A. 80 N.A. 93.3 93.3 N.A. 13.3 N.A. 60 26.6 N.A. 26.6 20 N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 28 37 0 0 10 0 0 10 10 0 0 19 10 0 % A
% Cys: 0 10 0 55 10 0 0 0 0 0 0 10 0 0 0 % C
% Asp: 0 0 0 0 10 0 0 0 0 19 10 64 28 10 0 % D
% Glu: 46 0 10 0 0 0 0 0 0 0 10 10 0 0 10 % E
% Phe: 0 0 0 10 28 64 0 10 55 0 0 0 0 0 10 % F
% Gly: 19 0 0 0 0 0 10 0 19 10 10 0 10 0 0 % G
% His: 0 10 0 10 0 0 0 0 10 0 0 0 0 0 0 % H
% Ile: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 10 10 0 0 0 0 0 0 19 0 0 0 0 % K
% Leu: 0 10 0 0 0 0 73 0 0 0 0 0 0 10 10 % L
% Met: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % M
% Asn: 10 0 0 10 0 0 0 0 0 0 0 0 19 0 0 % N
% Pro: 0 28 0 0 0 0 0 0 10 0 0 0 0 0 0 % P
% Gln: 10 0 0 0 0 10 0 10 0 0 0 0 10 55 10 % Q
% Arg: 0 0 0 0 0 0 0 0 0 10 46 10 0 0 0 % R
% Ser: 0 10 28 0 0 0 0 55 0 10 10 0 0 10 55 % S
% Thr: 0 0 0 0 10 10 0 0 0 46 0 0 0 0 10 % T
% Val: 0 10 10 10 46 10 10 10 0 0 0 10 10 0 0 % V
% Trp: 0 0 0 0 0 0 10 10 0 0 0 0 0 0 0 % W
% Tyr: 0 0 10 0 0 0 0 0 0 0 0 0 10 10 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _