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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TMEM195 All Species: 39.7
Human Site: T217 Identified Species: 79.39
UniProt: Q6ZNB7 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6ZNB7 NP_001004320.1 445 51500 T217 P L E L I L N T P S H H R V H
Chimpanzee Pan troglodytes XP_518978 445 51508 T217 P L E L I I N T P S H H R V H
Rhesus Macaque Macaca mulatta XP_001105641 445 51593 T217 P L E L I L N T P S H H R V H
Dog Lupus familis XP_532481 564 65047 T231 P L E L I I N T P S H H R V H
Cat Felis silvestris
Mouse Mus musculus Q8BS35 447 51759 T217 P L E V I L N T P S H H R V H
Rat Rattus norvegicus A0JPQ8 447 51680 T217 P L E L V L N T P S H H R V H
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511675 300 34982 V77 L T S L S A G V L S R L P S P
Chicken Gallus gallus XP_001235521 621 69043 T323 P L E W I L N T P S H H R V H
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q6NYE4 446 51779 T216 P L E L I L N T P S H H R V H
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_397032 321 38415 I98 E Y Y A Y I I I Y E K Y R L W
Nematode Worm Caenorhab. elegans O17554 505 58472 T230 P L G L V F N T P S H H R V H
Sea Urchin Strong. purpuratus XP_784522 447 52036 T214 P L E Y I L N T P S H H R V H
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 95 70.2 N.A. 83 82.7 N.A. 49.6 44.4 N.A. 58.9 N.A. N.A. 38.8 33.6 47.4
Protein Similarity: 100 100 97 73.7 N.A. 90.8 91.2 N.A. 57.5 53.6 N.A. 76.6 N.A. N.A. 51 52.2 65.5
P-Site Identity: 100 93.3 100 93.3 N.A. 93.3 93.3 N.A. 13.3 93.3 N.A. 100 N.A. N.A. 6.6 80 93.3
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 13.3 93.3 N.A. 100 N.A. N.A. 26.6 86.6 93.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 9 0 9 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 9 0 75 0 0 0 0 0 0 9 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 9 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 9 0 0 0 9 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 84 84 0 0 84 % H
% Ile: 0 0 0 0 67 25 9 9 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 9 0 0 0 0 % K
% Leu: 9 84 0 67 0 59 0 0 9 0 0 9 0 9 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 84 0 0 0 0 0 0 0 0 % N
% Pro: 84 0 0 0 0 0 0 0 84 0 0 0 9 0 9 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 9 0 92 0 0 % R
% Ser: 0 0 9 0 9 0 0 0 0 92 0 0 0 9 0 % S
% Thr: 0 9 0 0 0 0 0 84 0 0 0 0 0 0 0 % T
% Val: 0 0 0 9 17 0 0 9 0 0 0 0 0 84 0 % V
% Trp: 0 0 0 9 0 0 0 0 0 0 0 0 0 0 9 % W
% Tyr: 0 9 9 9 9 0 0 0 9 0 0 9 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _