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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM195
All Species:
34.55
Human Site:
T249
Identified Species:
69.09
UniProt:
Q6ZNB7
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6ZNB7
NP_001004320.1
445
51500
T249
I
W
D
K
I
F
G
T
F
E
A
E
N
E
K
Chimpanzee
Pan troglodytes
XP_518978
445
51508
T249
I
W
D
K
I
F
G
T
F
E
A
E
N
E
K
Rhesus Macaque
Macaca mulatta
XP_001105641
445
51593
T249
I
W
D
R
I
F
G
T
F
E
A
E
N
E
K
Dog
Lupus familis
XP_532481
564
65047
T263
I
W
D
R
I
F
G
T
F
E
A
E
N
E
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8BS35
447
51759
T249
I
W
D
R
I
F
G
T
F
E
A
E
N
E
Q
Rat
Rattus norvegicus
A0JPQ8
447
51680
T249
I
W
D
R
I
F
G
T
F
E
A
E
N
E
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511675
300
34982
P109
E
V
I
R
V
P
W
P
G
T
Y
T
W
Y
F
Chicken
Gallus gallus
XP_001235521
621
69043
A355
I
W
D
R
I
F
G
A
F
E
A
E
D
A
K
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q6NYE4
446
51779
T248
I
W
D
R
M
F
G
T
F
A
P
E
S
D
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_397032
321
38415
H130
D
F
C
Y
Y
W
V
H
R
S
N
H
E
V
H
Nematode Worm
Caenorhab. elegans
O17554
505
58472
T262
I
W
D
K
M
F
N
T
F
E
A
E
R
H
D
Sea Urchin
Strong. purpuratus
XP_784522
447
52036
T246
I
W
D
R
I
F
G
T
F
E
A
E
D
D
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
95
70.2
N.A.
83
82.7
N.A.
49.6
44.4
N.A.
58.9
N.A.
N.A.
38.8
33.6
47.4
Protein Similarity:
100
100
97
73.7
N.A.
90.8
91.2
N.A.
57.5
53.6
N.A.
76.6
N.A.
N.A.
51
52.2
65.5
P-Site Identity:
100
100
93.3
93.3
N.A.
86.6
86.6
N.A.
0
73.3
N.A.
60
N.A.
N.A.
0
66.6
73.3
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
13.3
86.6
N.A.
86.6
N.A.
N.A.
13.3
73.3
100
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
9
0
9
75
0
0
9
0
% A
% Cys:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
9
0
84
0
0
0
0
0
0
0
0
0
17
17
9
% D
% Glu:
9
0
0
0
0
0
0
0
0
75
0
84
9
50
0
% E
% Phe:
0
9
0
0
0
84
0
0
84
0
0
0
0
0
9
% F
% Gly:
0
0
0
0
0
0
75
0
9
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
9
0
0
0
9
0
9
9
% H
% Ile:
84
0
9
0
67
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
25
0
0
0
0
0
0
0
0
0
0
50
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
17
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
9
0
0
0
9
0
50
0
0
% N
% Pro:
0
0
0
0
0
9
0
9
0
0
9
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
17
% Q
% Arg:
0
0
0
67
0
0
0
0
9
0
0
0
9
0
9
% R
% Ser:
0
0
0
0
0
0
0
0
0
9
0
0
9
0
0
% S
% Thr:
0
0
0
0
0
0
0
75
0
9
0
9
0
0
0
% T
% Val:
0
9
0
0
9
0
9
0
0
0
0
0
0
9
0
% V
% Trp:
0
84
0
0
0
9
9
0
0
0
0
0
9
0
0
% W
% Tyr:
0
0
0
9
9
0
0
0
0
0
9
0
0
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _