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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM195
All Species:
33.94
Human Site:
Y259
Identified Species:
67.88
UniProt:
Q6ZNB7
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6ZNB7
NP_001004320.1
445
51500
Y259
A
E
N
E
K
V
V
Y
G
L
T
H
P
I
N
Chimpanzee
Pan troglodytes
XP_518978
445
51508
Y259
A
E
N
E
K
V
V
Y
G
L
T
H
P
I
N
Rhesus Macaque
Macaca mulatta
XP_001105641
445
51593
Y259
A
E
N
E
K
V
V
Y
G
L
T
H
P
I
N
Dog
Lupus familis
XP_532481
564
65047
Y273
A
E
N
E
K
V
V
Y
G
L
T
H
P
I
N
Cat
Felis silvestris
Mouse
Mus musculus
Q8BS35
447
51759
Y259
A
E
N
E
Q
V
I
Y
G
L
T
H
P
I
G
Rat
Rattus norvegicus
A0JPQ8
447
51680
Y259
A
E
N
E
Q
V
I
Y
G
L
T
H
P
I
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511675
300
34982
L119
Y
T
W
Y
F
T
V
L
S
S
G
V
D
T
G
Chicken
Gallus gallus
XP_001235521
621
69043
Y365
A
E
D
A
K
V
V
Y
G
L
T
H
P
V
N
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q6NYE4
446
51779
Y258
P
E
S
D
K
V
I
Y
G
L
T
H
P
I
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_397032
321
38415
W140
N
H
E
V
H
F
L
W
A
Q
H
Q
V
H
H
Nematode Worm
Caenorhab. elegans
O17554
505
58472
P272
A
E
R
H
D
D
P
P
I
Y
G
L
V
T
N
Sea Urchin
Strong. purpuratus
XP_784522
447
52036
Y256
A
E
D
D
R
V
A
Y
G
L
V
H
P
L
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
95
70.2
N.A.
83
82.7
N.A.
49.6
44.4
N.A.
58.9
N.A.
N.A.
38.8
33.6
47.4
Protein Similarity:
100
100
97
73.7
N.A.
90.8
91.2
N.A.
57.5
53.6
N.A.
76.6
N.A.
N.A.
51
52.2
65.5
P-Site Identity:
100
100
100
100
N.A.
80
80
N.A.
6.6
80
N.A.
66.6
N.A.
N.A.
0
20
53.3
P-Site Similarity:
100
100
100
100
N.A.
93.3
93.3
N.A.
6.6
93.3
N.A.
86.6
N.A.
N.A.
20
20
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
75
0
0
9
0
0
9
0
9
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
17
17
9
9
0
0
0
0
0
0
9
0
0
% D
% Glu:
0
84
9
50
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
9
9
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
75
0
17
0
0
0
34
% G
% His:
0
9
0
9
9
0
0
0
0
0
9
75
0
9
9
% H
% Ile:
0
0
0
0
0
0
25
0
9
0
0
0
0
59
0
% I
% Lys:
0
0
0
0
50
0
0
0
0
0
0
0
0
0
9
% K
% Leu:
0
0
0
0
0
0
9
9
0
75
0
9
0
9
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
9
0
50
0
0
0
0
0
0
0
0
0
0
0
50
% N
% Pro:
9
0
0
0
0
0
9
9
0
0
0
0
75
0
0
% P
% Gln:
0
0
0
0
17
0
0
0
0
9
0
9
0
0
0
% Q
% Arg:
0
0
9
0
9
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
9
0
0
0
0
0
9
9
0
0
0
0
0
% S
% Thr:
0
9
0
0
0
9
0
0
0
0
67
0
0
17
0
% T
% Val:
0
0
0
9
0
75
50
0
0
0
9
9
17
9
0
% V
% Trp:
0
0
9
0
0
0
0
9
0
0
0
0
0
0
0
% W
% Tyr:
9
0
0
9
0
0
0
75
0
9
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _