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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ZNF704 All Species: 7.88
Human Site: S374 Identified Species: 15.76
UniProt: Q6ZNC4 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6ZNC4 NP_001028895.1 412 45276 S374 S P P R G T V S L R K P R G E
Chimpanzee Pan troglodytes XP_519827 412 45270 S374 S P P R G T V S L R K P R G E
Rhesus Macaque Macaca mulatta XP_001091305 413 45411 V374 S S P P R G T V S L R K P R G
Dog Lupus familis XP_853536 429 46241 V390 S S P P R G T V S L R K P R G
Cat Felis silvestris
Mouse Mus musculus Q9ERQ3 566 61132 V527 S S P P R G T V T L R K P R G
Rat Rattus norvegicus XP_001056858 589 64354 V550 S S P P R G T V T L R K P R G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505447 420 45522 S374 Q H V Q A I L S S P P R G A F
Chicken Gallus gallus XP_418305 591 63973 G553 S P P R V A F G L R K P R G E
Frog Xenopus laevis Q6DFC8 498 54299 G466 N G N R K I R G E A K K C R K
Zebra Danio Brachydanio rerio Q1LY51 489 53922 G457 D R S R K S R G E G K K C R K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_001120785 577 63164 S539 S T G K M P S S P R R I R G E
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_782967 518 56769 L462 I A M W S S V L L V S S L F F
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 99.2 79 N.A. 64.3 63.1 N.A. 76.1 60.5 36.3 54.8 N.A. N.A. 20.4 N.A. 25.8
Protein Similarity: 100 99.7 99.5 81.5 N.A. 68.3 66.5 N.A. 81.9 64.6 51.4 63.7 N.A. N.A. 33.7 N.A. 41.5
P-Site Identity: 100 100 13.3 13.3 N.A. 13.3 13.3 N.A. 6.6 73.3 13.3 13.3 N.A. N.A. 40 N.A. 13.3
P-Site Similarity: 100 100 20 20 N.A. 20 20 N.A. 20 73.3 26.6 26.6 N.A. N.A. 53.3 N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 9 0 0 9 9 0 0 0 9 0 0 0 9 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 17 0 0 % C
% Asp: 9 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 17 0 0 0 0 0 34 % E
% Phe: 0 0 0 0 0 0 9 0 0 0 0 0 0 9 17 % F
% Gly: 0 9 9 0 17 34 0 25 0 9 0 0 9 34 34 % G
% His: 0 9 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 9 0 0 0 0 17 0 0 0 0 0 9 0 0 0 % I
% Lys: 0 0 0 9 17 0 0 0 0 0 42 50 0 0 17 % K
% Leu: 0 0 0 0 0 0 9 9 34 34 0 0 9 0 0 % L
% Met: 0 0 9 0 9 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 9 0 9 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 25 59 34 0 9 0 0 9 9 9 25 34 0 0 % P
% Gln: 9 0 0 9 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 9 0 42 34 0 17 0 0 34 42 9 34 50 0 % R
% Ser: 67 34 9 0 9 17 9 34 25 0 9 9 0 0 0 % S
% Thr: 0 9 0 0 0 17 34 0 17 0 0 0 0 0 0 % T
% Val: 0 0 9 0 9 0 25 34 0 9 0 0 0 0 0 % V
% Trp: 0 0 0 9 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _