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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NBEAL2 All Species: 7.58
Human Site: S2051 Identified Species: 15.15
UniProt: Q6ZNJ1 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.18
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6ZNJ1 NP_055990.1 2754 302517 S2051 P P S Q G Y L S S R S P Q E M
Chimpanzee Pan troglodytes XP_525997 2750 313008 G2046 R S P N S Y Y G S R S P Q E L
Rhesus Macaque Macaca mulatta XP_001094456 2295 260424 D1611 D Y T S E E L D L N N P A V F
Dog Lupus familis XP_541900 2305 251162 D1621 I A G R T Y N D L S Q Y P V F
Cat Felis silvestris
Mouse Mus musculus Q6ZQA0 2742 301906 S2039 P P T Q G Y L S S R S P L E M
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508701 2269 259447 S1585 L Q V C A M A S A K L N T L L
Chicken Gallus gallus XP_421964 2298 259902 W1614 A S G L M Q K W V N R E I S N
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9W4E2 3584 396477 L2594 L I N E G R L L S H A M K D H
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q19317 2507 281187 S1815 L P Q S R K T S L M T P R Q L
Sea Urchin Strong. purpuratus XP_785921 3355 375569 G2644 P P N L Y Y T G A K S P A D L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_182078 2946 321916 A2218 H L N N I Y L A T Q R P E Q L
Baker's Yeast Sacchar. cerevisiae P25356 2167 250854 F1483 K E R V S A F F S F Y N K R V
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 47.1 40.2 74.6 N.A. 88 N.A. N.A. 39.7 40.6 N.A. N.A. N.A. 20.7 N.A. 21.1 33.4
Protein Similarity: 100 65.6 56.3 77.1 N.A. 92 N.A. N.A. 53.8 55.7 N.A. N.A. N.A. 36.1 N.A. 37.4 48.8
P-Site Identity: 100 46.6 13.3 6.6 N.A. 86.6 N.A. N.A. 6.6 0 N.A. N.A. N.A. 20 N.A. 20 33.3
P-Site Similarity: 100 53.3 26.6 13.3 N.A. 93.3 N.A. N.A. 26.6 0 N.A. N.A. N.A. 53.3 N.A. 46.6 66.6
Percent
Protein Identity: N.A. N.A. N.A. 20.6 20.4 N.A.
Protein Similarity: N.A. N.A. N.A. 36.5 36.3 N.A.
P-Site Identity: N.A. N.A. N.A. 20 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 66.6 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 9 0 0 9 9 9 9 17 0 9 0 17 0 0 % A
% Cys: 0 0 0 9 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 9 0 0 0 0 0 0 17 0 0 0 0 0 17 0 % D
% Glu: 0 9 0 9 9 9 0 0 0 0 0 9 9 25 0 % E
% Phe: 0 0 0 0 0 0 9 9 0 9 0 0 0 0 17 % F
% Gly: 0 0 17 0 25 0 0 17 0 0 0 0 0 0 0 % G
% His: 9 0 0 0 0 0 0 0 0 9 0 0 0 0 9 % H
% Ile: 9 9 0 0 9 0 0 0 0 0 0 0 9 0 0 % I
% Lys: 9 0 0 0 0 9 9 0 0 17 0 0 17 0 0 % K
% Leu: 25 9 0 17 0 0 42 9 25 0 9 0 9 9 42 % L
% Met: 0 0 0 0 9 9 0 0 0 9 0 9 0 0 17 % M
% Asn: 0 0 25 17 0 0 9 0 0 17 9 17 0 0 9 % N
% Pro: 25 34 9 0 0 0 0 0 0 0 0 59 9 0 0 % P
% Gln: 0 9 9 17 0 9 0 0 0 9 9 0 17 17 0 % Q
% Arg: 9 0 9 9 9 9 0 0 0 25 17 0 9 9 0 % R
% Ser: 0 17 9 17 17 0 0 34 42 9 34 0 0 9 0 % S
% Thr: 0 0 17 0 9 0 17 0 9 0 9 0 9 0 0 % T
% Val: 0 0 9 9 0 0 0 0 9 0 0 0 0 17 9 % V
% Trp: 0 0 0 0 0 0 0 9 0 0 0 0 0 0 0 % W
% Tyr: 0 9 0 0 9 50 9 0 0 0 9 9 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _