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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NBEAL2 All Species: 17.58
Human Site: S2108 Identified Species: 35.15
UniProt: Q6ZNJ1 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6ZNJ1 NP_055990.1 2754 302517 S2108 W V L Q D Y V S P T L D L S N
Chimpanzee Pan troglodytes XP_525997 2750 313008 S2103 W I L Q D Y T S E E L D L N N
Rhesus Macaque Macaca mulatta XP_001094456 2295 260424 Y1668 N S A G V M H Y L I R V E P F
Dog Lupus familis XP_541900 2305 251162 G1678 E S F E D P A G T I D K F H Y
Cat Felis silvestris
Mouse Mus musculus Q6ZQA0 2742 301906 S2096 W V L Q D Y V S P V L D L S N
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508701 2269 259447 L1642 L V S K I Y E L L F M N L H L
Chicken Gallus gallus XP_421964 2298 259902 P1671 V F R D L S K P I G V V N E K
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9W4E2 3584 396477 A2651 M C D H L I T A A R R R D N V
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q19317 2507 281187 S1872 W I L T N Y T S D T L D L S V
Sea Urchin Strong. purpuratus XP_785921 3355 375569 S2701 W I L S D Y S S E E L D L E N
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_182078 2946 321916 S2275 W I I S D N S S E S L D L S N
Baker's Yeast Sacchar. cerevisiae P25356 2167 250854 F1540 K A S I A S K F T S V F S A N
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 47.1 40.2 74.6 N.A. 88 N.A. N.A. 39.7 40.6 N.A. N.A. N.A. 20.7 N.A. 21.1 33.4
Protein Similarity: 100 65.6 56.3 77.1 N.A. 92 N.A. N.A. 53.8 55.7 N.A. N.A. N.A. 36.1 N.A. 37.4 48.8
P-Site Identity: 100 66.6 0 6.6 N.A. 93.3 N.A. N.A. 20 0 N.A. N.A. N.A. 0 N.A. 60 60
P-Site Similarity: 100 80 0 13.3 N.A. 93.3 N.A. N.A. 40 6.6 N.A. N.A. N.A. 13.3 N.A. 73.3 66.6
Percent
Protein Identity: N.A. N.A. N.A. 20.6 20.4 N.A.
Protein Similarity: N.A. N.A. N.A. 36.5 36.3 N.A.
P-Site Identity: N.A. N.A. N.A. 53.3 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 73.3 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 9 9 0 9 0 9 9 9 0 0 0 0 9 0 % A
% Cys: 0 9 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 9 9 50 0 0 0 9 0 9 50 9 0 0 % D
% Glu: 9 0 0 9 0 0 9 0 25 17 0 0 9 17 0 % E
% Phe: 0 9 9 0 0 0 0 9 0 9 0 9 9 0 9 % F
% Gly: 0 0 0 9 0 0 0 9 0 9 0 0 0 0 0 % G
% His: 0 0 0 9 0 0 9 0 0 0 0 0 0 17 0 % H
% Ile: 0 34 9 9 9 9 0 0 9 17 0 0 0 0 0 % I
% Lys: 9 0 0 9 0 0 17 0 0 0 0 9 0 0 9 % K
% Leu: 9 0 42 0 17 0 0 9 17 0 50 0 59 0 9 % L
% Met: 9 0 0 0 0 9 0 0 0 0 9 0 0 0 0 % M
% Asn: 9 0 0 0 9 9 0 0 0 0 0 9 9 17 50 % N
% Pro: 0 0 0 0 0 9 0 9 17 0 0 0 0 9 0 % P
% Gln: 0 0 0 25 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 9 0 0 0 0 0 0 9 17 9 0 0 0 % R
% Ser: 0 17 17 17 0 17 17 50 0 17 0 0 9 34 0 % S
% Thr: 0 0 0 9 0 0 25 0 17 17 0 0 0 0 0 % T
% Val: 9 25 0 0 9 0 17 0 0 9 17 17 0 0 17 % V
% Trp: 50 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 50 0 9 0 0 0 0 0 0 9 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _