Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NBEAL2 All Species: 20.91
Human Site: S2269 Identified Species: 41.82
UniProt: Q6ZNJ1 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6ZNJ1 NP_055990.1 2754 302517 S2269 Q H R Q A L E S E Y V S A H L
Chimpanzee Pan troglodytes XP_525997 2750 313008 S2264 K H R K A L E S E Y V S A H L
Rhesus Macaque Macaca mulatta XP_001094456 2295 260424 L1822 D E K E R K A L E G M I N N F
Dog Lupus familis XP_541900 2305 251162 C1832 A L N V F Y Y C T Y E G A V D
Cat Felis silvestris
Mouse Mus musculus Q6ZQA0 2742 301906 S2257 K H R Q A L E S E Y V S T H L
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508701 2269 259447 V1796 I H W K L A T V E N Y S R M R
Chicken Gallus gallus XP_421964 2298 259902 W1825 V S A H L H E W I D L I F G Y
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9W4E2 3584 396477 I2898 L P R V G V G I K Y G I P Q T
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q19317 2507 281187 S2030 M H R Q A L E S D L V S C Q L
Sea Urchin Strong. purpuratus XP_785921 3355 375569 S2861 K H R Q A L E S D Y V S S H L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_182078 2946 321916 S2433 K Q R R A L E S E H V S A H L
Baker's Yeast Sacchar. cerevisiae P25356 2167 250854 A1694 L F S S L E R A W S S A S S E
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 47.1 40.2 74.6 N.A. 88 N.A. N.A. 39.7 40.6 N.A. N.A. N.A. 20.7 N.A. 21.1 33.4
Protein Similarity: 100 65.6 56.3 77.1 N.A. 92 N.A. N.A. 53.8 55.7 N.A. N.A. N.A. 36.1 N.A. 37.4 48.8
P-Site Identity: 100 86.6 6.6 13.3 N.A. 86.6 N.A. N.A. 20 6.6 N.A. N.A. N.A. 13.3 N.A. 66.6 80
P-Site Similarity: 100 100 33.3 13.3 N.A. 93.3 N.A. N.A. 26.6 13.3 N.A. N.A. N.A. 26.6 N.A. 73.3 100
Percent
Protein Identity: N.A. N.A. N.A. 20.6 20.4 N.A.
Protein Similarity: N.A. N.A. N.A. 36.5 36.3 N.A.
P-Site Identity: N.A. N.A. N.A. 73.3 0 N.A.
P-Site Similarity: N.A. N.A. N.A. 93.3 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 0 9 0 50 9 9 9 0 0 0 9 34 0 0 % A
% Cys: 0 0 0 0 0 0 0 9 0 0 0 0 9 0 0 % C
% Asp: 9 0 0 0 0 0 0 0 17 9 0 0 0 0 9 % D
% Glu: 0 9 0 9 0 9 59 0 50 0 9 0 0 0 9 % E
% Phe: 0 9 0 0 9 0 0 0 0 0 0 0 9 0 9 % F
% Gly: 0 0 0 0 9 0 9 0 0 9 9 9 0 9 0 % G
% His: 0 50 0 9 0 9 0 0 0 9 0 0 0 42 0 % H
% Ile: 9 0 0 0 0 0 0 9 9 0 0 25 0 0 0 % I
% Lys: 34 0 9 17 0 9 0 0 9 0 0 0 0 0 0 % K
% Leu: 17 9 0 0 25 50 0 9 0 9 9 0 0 0 50 % L
% Met: 9 0 0 0 0 0 0 0 0 0 9 0 0 9 0 % M
% Asn: 0 0 9 0 0 0 0 0 0 9 0 0 9 9 0 % N
% Pro: 0 9 0 0 0 0 0 0 0 0 0 0 9 0 0 % P
% Gln: 9 9 0 34 0 0 0 0 0 0 0 0 0 17 0 % Q
% Arg: 0 0 59 9 9 0 9 0 0 0 0 0 9 0 9 % R
% Ser: 0 9 9 9 0 0 0 50 0 9 9 59 17 9 0 % S
% Thr: 0 0 0 0 0 0 9 0 9 0 0 0 9 0 9 % T
% Val: 9 0 0 17 0 9 0 9 0 0 50 0 0 9 0 % V
% Trp: 0 0 9 0 0 0 0 9 9 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 9 9 0 0 50 9 0 0 0 9 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _