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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NBEAL2
All Species:
6.67
Human Site:
S2643
Identified Species:
13.33
UniProt:
Q6ZNJ1
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6ZNJ1
NP_055990.1
2754
302517
S2643
V
N
G
K
L
R
A
S
L
P
L
A
E
Q
P
Chimpanzee
Pan troglodytes
XP_525997
2750
313008
S2639
I
N
G
K
Y
L
G
S
Q
I
L
K
E
Q
V
Rhesus Macaque
Macaca mulatta
XP_001094456
2295
260424
H2191
L
A
M
R
L
P
I
H
C
V
C
V
T
K
E
Dog
Lupus familis
XP_541900
2305
251162
L2201
A
Q
C
A
L
H
I
L
H
L
N
K
L
L
P
Cat
Felis silvestris
Mouse
Mus musculus
Q6ZQA0
2742
301906
S2631
V
N
G
R
L
R
A
S
V
T
L
T
E
Q
P
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508701
2269
259447
G2165
N
Q
N
Q
F
N
L
G
R
L
Q
V
S
K
E
Chicken
Gallus gallus
XP_421964
2298
259902
K2194
H
L
G
S
E
T
L
K
E
E
V
S
D
M
C
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W4E2
3584
396477
N3322
Q
M
L
K
I
R
S
N
C
F
V
T
T
V
D
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q19317
2507
281187
E2403
A
T
A
K
K
L
D
E
V
L
V
D
D
K
I
Sea Urchin
Strong. purpuratus
XP_785921
3355
375569
P3243
S
A
A
S
K
P
A
P
D
H
C
S
L
H
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_182078
2946
321916
I2813
W
S
S
S
E
G
S
I
S
V
F
T
I
N
G
Baker's Yeast
Sacchar. cerevisiae
P25356
2167
250854
S2063
F
E
P
A
K
I
V
S
S
I
D
F
F
D
F
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
47.1
40.2
74.6
N.A.
88
N.A.
N.A.
39.7
40.6
N.A.
N.A.
N.A.
20.7
N.A.
21.1
33.4
Protein Similarity:
100
65.6
56.3
77.1
N.A.
92
N.A.
N.A.
53.8
55.7
N.A.
N.A.
N.A.
36.1
N.A.
37.4
48.8
P-Site Identity:
100
46.6
6.6
13.3
N.A.
73.3
N.A.
N.A.
0
6.6
N.A.
N.A.
N.A.
13.3
N.A.
6.6
6.6
P-Site Similarity:
100
53.3
26.6
13.3
N.A.
86.6
N.A.
N.A.
13.3
26.6
N.A.
N.A.
N.A.
40
N.A.
33.3
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.6
20.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
36.5
36.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
17
17
17
17
0
0
25
0
0
0
0
9
0
0
0
% A
% Cys:
0
0
9
0
0
0
0
0
17
0
17
0
0
0
9
% C
% Asp:
0
0
0
0
0
0
9
0
9
0
9
9
17
9
9
% D
% Glu:
0
9
0
0
17
0
0
9
9
9
0
0
25
0
17
% E
% Phe:
9
0
0
0
9
0
0
0
0
9
9
9
9
0
9
% F
% Gly:
0
0
34
0
0
9
9
9
0
0
0
0
0
0
9
% G
% His:
9
0
0
0
0
9
0
9
9
9
0
0
0
9
0
% H
% Ile:
9
0
0
0
9
9
17
9
0
17
0
0
9
0
9
% I
% Lys:
0
0
0
34
25
0
0
9
0
0
0
17
0
25
0
% K
% Leu:
9
9
9
0
34
17
17
9
9
25
25
0
17
9
9
% L
% Met:
0
9
9
0
0
0
0
0
0
0
0
0
0
9
0
% M
% Asn:
9
25
9
0
0
9
0
9
0
0
9
0
0
9
0
% N
% Pro:
0
0
9
0
0
17
0
9
0
9
0
0
0
0
25
% P
% Gln:
9
17
0
9
0
0
0
0
9
0
9
0
0
25
0
% Q
% Arg:
0
0
0
17
0
25
0
0
9
0
0
0
0
0
0
% R
% Ser:
9
9
9
25
0
0
17
34
17
0
0
17
9
0
0
% S
% Thr:
0
9
0
0
0
9
0
0
0
9
0
25
17
0
0
% T
% Val:
17
0
0
0
0
0
9
0
17
17
25
17
0
9
9
% V
% Trp:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _